Substance / Medication

Cerivastatin

SNOMED 373443008 UMLS C0528023

Overview

Active Ingredient

cerivastatin

RxNorm CUI

596723

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Hyperlipoproteinemia

Hypercholesterolemia

Hypertriglyceridaemia

Disorder of coronary artery

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Adductor Canal Block After Total Knee Replacement - a Suture-method Catheter vs a Standard Catheter vs a Single Bolus

NCT03142789Phase 4Completed153 enrolled

View all 1 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Cerivastatin for lowering lipids.

Adams Stephen P, Tiellet Nicholas, Alaeiilkhchi Nima et al. · Cochrane Database Syst Rev · 2020

PMID: 31981471Meta-AnalysisFull text (PMC)

The effect of cerivastatin therapy on vascular responses to endothelin antagonists in humans.

Leslie Stephen J, Spratt James C, Grieg Lynn et al. · J Cardiovasc Pharmacol · 2004

PMID: 15838335RCT

Polymer-free cerivastatin-eluting stent shows superior neointimal inhibition with preserved vasomotor function compared to polymer-based paclitaxel-eluting stent in rabbit iliac arteries.

Pendyala Lakshmana, Yin Xinhua, Li Jinsheng et al. · EuroIntervention · 2010

PMID: 20542808Observational

The HMG-CoA reductase inhibitor cerivastatin lowers advanced glycation end products in patients with type 2 diabetes.

Scharnagl H, Stojakovic T, Winkler K et al. · Exp Clin Endocrinol Diabetes · 2007

PMID: 17701882Observational

Combination therapy with cerivastatin and nifedipine improves endothelial dysfunction after balloon injury in porcine coronary arteries.

Eto Yasuhiro, Shimokawa Hiroaki, Fukumoto Yoshihiro et al. · J Cardiovasc Pharmacol · 2005

PMID: 15965348Observational

Site-specific effects of cerivastatin on bone in male Sprague-Dawley rats.

Banu Jameela, Kalu Dike N · Bone · 2004

PMID: 15003791Observational

Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats.

Schaefer William H, Lawrence Jeffery W, Loughlin Amy F et al. · Toxicol Appl Pharmacol · 2004

PMID: 14728975Observational

The cerivastatin withdrawal crisis: a "post-mortem" analysis.

Maggini Marina, Raschetti Roberto, Traversa Giuseppe et al. · Health Policy · 2004

PMID: 15212862Observational

Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice.

Kivistö Kari T, Zukunft Jörg, Hofmann Ute et al. · Naunyn Schmiedebergs Arch Pharmacol · 2004

PMID: 15322734Observational

Cerivastatin inhibits proliferation of interleukin-1 beta-induced rat mesangial cells by enhanced formation of nitric oxide.

Blume Cornelia, Sabuda-Widemann Danuta, Pfeilschifter Josef et al. · Eur J Pharmacol · 2004

PMID: 14757118Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Cerivastatin (substance)
SNOMED CT: 373443008
UMLS CUI: C0528023
RxNorm CUI: 596723

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.