Substance / Medication

Cetuximab

Overview

Active Ingredient
cetuximab
RxNorm CUI
318341
Labeler: ImClone LLCUpdated: 2024-07-25T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Infusion Reactions: ERBITUX can cause serious and fatal infusion reactions 5.1 6 [see Warnings and Precautions (), Adverse Reactions ()] . Immediately interrupt and permanently discontinue ERBITUX for serious infusion reactions 2.5 [see Dosage and Administration ()] . Cardiopulmonary Arrest: Cardiop

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

24 trials linked to this intervention

24
Total Trials
23
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Targeted doublet therapy with encorafenib and cetuximab for BRAF V600E-mutant metastatic colorectal cancer: A systematic review and meta-analysis.
Ansab Muhammad, Rath Shree, Araib Eiman et al. · Crit Rev Oncol Hematol · 2025
PMID: 40976455Meta-Analysis
A comparison of panitumumab and cetuximab in the treatment of KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis.
Liu Tong, Jiang Shuai, Teng Xue et al. · Immunopharmacol Immunotoxicol · 2023
PMID: 35950851Meta-Analysis
Chemotherapy plus panitumumab/cetuximab versus chemotherapy plus bevacizumab in wild-type KRAS/RAS metastatic colorectal cancer: a meta-analysis.
Zhang Chengren, Liu Lili, Lv Yaochun et al. · Expert Rev Anticancer Ther · 2022
PMID: 36374121Meta-Analysis
Efficacy and Safety of Cetuximab Dosing (biweekly vs weekly) in Patients with KRAS Wild-type Metastatic Colorectal Cancer: A Meta-analysis.
Parikh Aparna R, Gonzalez-Gugel Elena, Smolyakova Natalia et al. · Oncologist · 2022
PMID: 35522557Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cetuximab (substance)
SNOMED CT
409400001
UMLS CUI
C0995188
RxNorm CUI
318341
Labeler
ImClone LLC

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
24
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.