Substance / Medication

Cilastatin sodium

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

101 trials linked to this intervention

101
Total Trials
28
Recruiting
8
With Results

Research Evidence

Published studies and systematic reviews

Sort:
[Domestic imipenem cilastatin sodium for the treatment of severe aspiration pneumonia, a curative effect observation].
Yin Hai-yan, Ye Xiao-ling, Zhang Rui et al. · Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · 2012
PMID: 23040783RCT
Spectrophotometric and chemometric methods for determination of imipenem, ciprofloxacin hydrochloride, dexamethasone sodium phosphate, paracetamol and cilastatin sodium in human urine.
El-Kosasy A M, Abdel-Aziz Omar, Magdy N et al. · Spectrochim Acta A Mol Biomol Spectrosc · 2016
PMID: 26709018Observational
Imipenem cilastatin sodium-associated thrombocytopenia in an older patient: A case report and literature review.
Qiao Weizhen, Chang Chunyan, Wang Qiuhui et al. · Int J Clin Pharmacol Ther · 2022
PMID: 35652550Case Report
Transcatheter arterial embolization using imipenem/cilastatin sodium and microspheres for traumatic pseudoaneurysm: A case report.
Hirano Takaki, Iwasaki Yudai, Ishida Tokiya et al. · Trauma Case Rep · 2022
PMID: 36247878Case ReportFull text (PMC)
Analgesic effects of intraarterial injection of imipenem/cilastatin sodium in a rat model of knee osteoarthritis.
Matsuyama Yuki, Yamanaka Manabu, Taniguchi Wataru et al. · Neuroscience · 2025
PMID: 39978671Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cilastatin sodium (substance)
SNOMED CT
734464004
UMLS CUI
C0282395

Clinical Data

This intervention maps to 8 entities in the Ltrl knowledge graph.

8
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
101
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.