Substance / Medication

Cinacalcet

Overview

Active Ingredient
cinacalcet
RxNorm CUI
407990

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

20 trials linked to this intervention

20
Total Trials
1
Recruiting
7
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Safety of cinacalcet in children and adolescents with chronic kidney disease-mineral bone disorder: systematic review and proportional meta-analysis of case series.
Zamoner Soraya Mayumi Sasaoka, Takase Henrique Mochida, Riyuzo Marcia Camegaçava et al. · Int Urol Nephrol · 2024
PMID: 37964112Meta-AnalysisFull text (PMC)
Cinacalcet use in secondary hyperparathyroidism: a machine learning-based systematic review.
Li Xiaosong, Ding Wei, Zhang Hong · Front Endocrinol (Lausanne) · 2023
PMID: 37538795Meta-AnalysisFull text (PMC)
The efficacy and safety of cinacalcet in primary hyperparathyroidism: a systematic review and meta-analysis of randomized controlled trials and cohort studies.
Chandran Manju, Bilezikian John P, Lau Joel et al. · Rev Endocr Metab Disord · 2022
PMID: 35041148Meta-Analysis
Parathyroidectomy or cinacalcet: Do we still not know the best option for graft function in kidney-transplanted patients? A meta-analysis.
Frey Samuel, Goronflot Thomas, Kerleau Clarisse et al. · Surgery · 2021
PMID: 33810851Meta-Analysis
Cinacalcet Treatment Significantly Improves All-Cause and Cardiovascular Survival in Dialysis Patients: Results from a Meta-Analysis.
Zu Yuan, Lu Xiangxue, Song Jinghong et al. · Kidney Blood Press Res · 2019
PMID: 31747666Meta-Analysis
The use of cinacalcet for the treatment of calciphylaxis in patients with chronic kidney disease: A comprehensive review.
Deen Jacqueline, Schaider Helmut · Australas J Dermatol · 2019
PMID: 30666627Meta-Analysis
Cinacalcet for Treatment of Chronic Kidney Disease-Mineral and Bone Disorder: A Meta-Analysis of Randomized Controlled Trials.
Greeviroj Primploy, Kitrungphaiboon Thidarat, Katavetin Pisut et al. · Nephron · 2018
PMID: 29514156Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cinacalcet (substance)
SNOMED CT
409392004
UMLS CUI
C1337242
RxNorm CUI
407990

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
20
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.