Substance / Medication

Cloxacillin

Overview

Active Ingredient
cloxacillin
RxNorm CUI
2625

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

38 trials linked to this intervention

38
Total Trials
2
Recruiting
12
With Results

Research Evidence

Published studies and systematic reviews

Sort:
A meta-analysis of protein binding of flucloxacillin in healthy volunteers and hospitalized patients.
Wallenburg Eveline, Brüggemann Roger J M, Roberts Jason A et al. · Clin Microbiol Infect · 2022
PMID: 34245903Meta-Analysis
Flucloxacillin Is a Weak Inducer of CYP3A4 in Healthy Adults and 3D Spheroid of Primary Human Hepatocytes.
Iversen Ditte B, Dunvald Ann-Cathrine Dalgård, Jespersen Daniel M et al. · Clin Pharmacol Ther · 2023
PMID: 37235733RCT
A Population Pharmacokinetic Analysis of Continuous Infusion of Cloxacillin duringBone and Joint Infections.
Courjon Johan, Garzaro Margaux, Roger Pierre-Marie et al. · Antimicrob Agents Chemother · 2020
PMID: 32988822RCTFull text (PMC)
Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro.
Stage Tore Bjerregaard, Graff Magnus, Wong Susan et al. · Br J Clin Pharmacol · 2018
PMID: 29105855RCTFull text (PMC)
A randomized prospective study of prophylactic cloxacillin in breast reduction surgery.
Lewin Richard, Elander Anna, Thorarinsson Andri et al. · Ann Plast Surg · 2015
PMID: 25305230RCT
Safety and pharmacokinetics of dicloxacillin in healthy Chinese volunteers following single and multiple oral doses.
Wu Guolan, Zheng Yunliang, Zhou Huili et al. · Drug Des Devel Ther · 2015
PMID: 26527863RCTFull text (PMC)
Cloxacillin concentrations in serum, subcutaneous fat, and muscle in patients with chronic critical limb ischemia.
Jonsson T B, Nilsson T K, Breimer L H et al. · Eur J Clin Pharmacol · 2014
PMID: 24858821RCT
Flucloxacillin and diclofenac do not cause recurrence of neuromuscular blockade after reversal with sugammadex.
Kam Pieter-Jan de, Heuvel Michiel W van den, Grobara Peter et al. · Clin Drug Investig · 2012
PMID: 22201295RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cloxacillin (substance)
SNOMED CT
373276005
UMLS CUI
C0009077
RxNorm CUI
2625

Clinical Data

This intervention maps to 8 entities in the Ltrl knowledge graph.

8
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
38
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.