Substance / Medication

Crotamiton

Overview

Active Ingredient
crotamiton
RxNorm CUI
21766

Indications

INDICATIONS AND USAGE: Sarcoptes scabiei For eradication of scabies () and for symptomatic treatment of pruritic skin.

Labeler: Trifluent Pharma, LLCUpdated: 2025-06-02T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

CONTRAINDICATIONS: Pruradik lotion should not be applied topically to patients who develop a sensitivity or are allergic to it or who manifest a primary irritation response to topical medications.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

5 trials linked to this intervention

5
Total Trials
2
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Treatment of scabies, permethrin 5% cream vs. crotamiton 10% cream.
Pourhasan Abolfazl, Goldust Mohamad, Rezaee Elham · Ann Parasitol · 2013
PMID: 24881286RCT
Topical ivermectin versus crotamiton cream 10% for the treatment of scabies.
Goldust Mohamad, Rezaee Elham, Raghiafar Ramin · Int J Dermatol · 2014
PMID: 24898622Observational
Comparison of oral ivermectin versus crotamiton 10% cream in the treatment of scabies.
Goldust Mohamad, Rezaee Elham, Raghifar Ramin · Cutan Ocul Toxicol · 2014
PMID: 23431958Observational
Anogenital skin necrosis with fibrin thrombosis induced by crotamiton.
Handa Toshiya, Kamiya Takafumi, Kan Yuji et al. · Contact Dermatitis · 2022
PMID: 34729785Case Report
Triple allergic contact sensitivities due to ferbinac, crotamiton and diisopropanolamine.
Oiso Naoki, Fukai Kazuyoshi, Ishii Masamitsu · Contact Dermatitis · 2003
PMID: 14996052Case Report
Allergic contact dermatitis due to crotamiton.
Hara H, Masuda T, Yokoyama A et al. · Contact Dermatitis · 2003
PMID: 14996078Case Report
Concomitant allergic reaction to cetyl alcohol and crotamiton.
Oiso Naoki, Fukai Kazuyoshi, Ishii Masamitsu · Contact Dermatitis · 2003
PMID: 14996053Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Crotamiton (substance)
SNOMED CT
387515007
UMLS CUI
C0056519
RxNorm CUI
21766
Labeler
Trifluent Pharma, LLC

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
5
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.