Substance / Medication

Dextran

Overview

Active Ingredient
dextran
RxNorm CUI
42635

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Dextran as an Adjunct in Carotid Endarterectomy: A Systematic Review and Meta-Analysis.
Silva-Vieira Duarte, Pereira-Neves António, Nzwalo Hipolito et al. · Ann Vasc Surg · 2025
PMID: 40582452Meta-Analysis
Recent Advances of Pullulan and/or Dextran-Based Materials for Bone Tissue Engineering Strategies in Preclinical Studies: A Systematic Review.
Ahmed Omar Naïma, Amédée Joëlle, Letourneur Didier et al. · Front Bioeng Biotechnol · 2022
PMID: 35845411Meta-AnalysisFull text (PMC)
7.5% saline and 7.5% saline/6% dextran for hypovolemic shock.
Bulger Eileen M · J Trauma · 2011
PMID: 21666775Meta-AnalysisFull text (PMC)
Dextranomer/hyaluronic acid for pediatric vesicoureteral reflux: systematic review.
Routh Jonathan C, Inman Brant A, Reinberg Yuri · Pediatrics · 2010
PMID: 20368325Meta-Analysis
Efficacy of hypertonic saline dextran fluid resuscitation for patients with hypotension from penetrating trauma.
Wade Charles E, Grady J J, Kramer George C · J Trauma · 2003
PMID: 12768117Meta-Analysis
Dextran vs. Crystalloid Priming Solution in Cardiac Surgery: A Randomized Trial on Acute Kidney Injury.
Juvakka Oskar, Wallinder Andreas, Møller-Sørensen Peter Hasse et al. · Acta Anaesthesiol Scand · 2026
PMID: 41144782RCTFull text (PMC)
Hemostatic effects of a dextran-based priming solution for cardiopulmonary bypass: A secondary analysis of a randomized clinical trial.
Barbu Mikael, Kolsrud Oscar, Radulovic Vladimir et al. · Thromb Res · 2023
PMID: 36753875RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Dextran (substance)
SNOMED CT
372650007
UMLS CUI
C0086140
RxNorm CUI
42635

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.