Substance / Medication

Difenidol

Overview

Active Ingredient
diphenidol
RxNorm CUI
23370

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

63 trials linked to this intervention

63
Total Trials
5
Recruiting
21
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Comparison of the antimuscarinic action of p-fluorohexahydrosiladifenidol in ileal and tracheal smooth muscle.
Ehlert Frederick J, Hsu Jake Ching-Hsuan, Leung Kevin et al. · J Pharmacol Exp Ther · 2005
PMID: 15456838Observational
[Death caused by high-dose difenidol hydrochloride combined with ethanol and potassium chloride poisoning: A case report].
Gao Rihong, Wang Xinzhou, Wang Bing et al. · Fa Yi Xue Za Zhi · 2023
PMID: 38006274Case Report
Electrochemiluminescence Sensor based on Electrospun Crosslinked Carbon Nanofibers for the Detection of Difenidol Hydrochloride.
Cheng Hao, Li Xuenuan, Li Tianhao et al. · Comb Chem High Throughput Screen · 2023
PMID: 35611783Other
Determination of difenidol hydrochloride by capillary electrophoresis with electrochemiluminescence detection.
Pan Wen, Liu Yingju, Huang Yan et al. · J Chromatogr B Analyt Technol Biomed Life Sci · 2006
PMID: 16364700Other
Forensic toxicokinetics of difenidol hydrochloride in vivo verified by practical lethal cases.
Niu Weifen, Ren Tongxi, Wang Yandan et al. · Sci Rep · 2023
PMID: 37433899PreclinicalFull text (PMC)
Blockade of voltage-gated calcium channel Cav1.2 and α1-adrenoceptors increases vertebral artery blood flow induced by the antivertigo agent difenidol.
Murakami Kohji, Inoue Naoki, Fuchikami Chiaki et al. · Eur J Pharmacol · 2012
PMID: 22683869Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Difenidol (substance)
SNOMED CT
63779001
UMLS CUI
C0058371
RxNorm CUI
23370

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
63
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.