Substance / Medication

Dimeticone

Overview

Active Ingredient
dimethicone
RxNorm CUI
324072

Indications

Diabecin HR™ Cream is indicated for the temporary relief of pain and itching associated with minor skin irritations. It combines the anesthetic properties of Lidocaine, and the antiseptic effects of Benzalkonium Chloride to provide effective care for damaged skin.

Labeler: PureTek CorporationUpdated: 2025-06-10T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Tuberculosis or fungal lesions of the skin vaccinia, varicella and acute herpes simplex and in persons who have shown hypersensitivity to any of its components. Lidocaine is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Treatment of Tungiasis with dimeticone: a proof-of-principle study in rural Kenya.
Thielecke Marlene, Nordin Per, Ngomi Nicholas et al. · PLoS Negl Trop Dis · 2014
PMID: 25079375RCTFull text (PMC)
Effect of dimeticone and pepsin on the bioavailability of metoclopramide in healthy volunteers.
do Nascimento D F, Silva Leite A L A e, de Moraes R A et al. · Drug Res (Stuttg) · 2014
PMID: 24504688RCT
Comparing the Efficacy of Commercially Available Insecticide and Dimeticone based Solutions on Head Lice, Pediculus capitis: in vitro Trials.
Balcıoğlu I Cüneyt, Karakuş Mehmet, Arserim Suha K et al. · Turkiye Parazitol Derg · 2015
PMID: 26809918Observational
Treatment of head lice with dimeticone 4% lotion: comparison of two formulations in a randomised controlled trial in rural Turkey.
Kurt Ozgür, Balcioğlu I Cüneyt, Burgess Ian F et al. · BMC Public Health · 2009
PMID: 19951427ObservationalFull text (PMC)
A new two-phase dimeticone pediculicide shows high efficacy in a comparative bioassay.
Heukelbach Jorg, Asenov André, Liesenfeld Oliver et al. · BMC Dermatol · 2009
PMID: 20003435ObservationalFull text (PMC)
A highly efficacious pediculicide based on dimeticone: randomized observer blinded comparative trial.
Heukelbach Jorg, Pilger Daniel, Oliveira Fabíola A et al. · BMC Infect Dis · 2008
PMID: 18783606ObservationalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Dimeticone (substance)
SNOMED CT
396031000
UMLS CUI
C1113707
RxNorm CUI
324072
Labeler
PureTek Corporation

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Dimeticone — Conditions, Biomarkers & Specialists | Ltrl | Healos