Substance / Medication

dl-alpha-tocopheryl acetate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Alzheimer's disease

Vitamin E deficiency

Hemolytic anemia

Drug-induced dyskinesia

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:

Vitamin E supplementation in people with cystic fibrosis.

Okebukola Peter O, Kansra Sonal, Barrett Joanne · Cochrane Database Syst Rev · 2017

PMID: 28262916Meta-AnalysisFull text (PMC)

Vitamin E supplementation in people with cystic fibrosis.

Okebukola Peter O, Kansra Sonal, Barrett Joanne · Cochrane Database Syst Rev · 2014

PMID: 25489958Meta-Analysis

Effects of vitamin E supplementation on glycaemic control in type 2 diabetes: systematic review of randomized controlled trials.

Suksomboon N, Poolsup N, Sinprasert S · J Clin Pharm Ther · 2011

PMID: 21198720Meta-Analysis

Risk of inadequate intakes of vitamins A, B1, B6, C, E, folate, iron and calcium in the Spanish population aged 4 to 18.

Serra-Majem L, Ribas L, Ngo J et al. · Int J Vitam Nutr Res · 2001

PMID: 11840835Meta-Analysis

Effects of feeding two RRR-α-tocopherol formulations on serum, cerebrospinal fluid and muscle α-tocopherol concentrations in horses with subclinical vitamin E deficiency.

Brown J C, Valberg S J, Hogg M et al. · Equine Vet J · 2017

PMID: 28432750RCTFull text (PMC)

Potential use of 2-hydroxypropyl-beta-cyclodextrin for preparation of orally disintegrating tablets containing dl-alpha-tocopheryl acetate, an oily drug.

Motoyama Keiichi, Nagatomo Kiyoshi, Abd Elazim Soliman Osama et al. · Chem Pharm Bull (Tokyo) · 2009

PMID: 19881268Other

Incorporation of alpha-tocopherol and linoleic acid in fresh lambs by feeding chemically treated dietary supplements containing dl-alpha-tocopheryl acetate and sunflower oil.

Lee Jung Hoon, Waller John C, Melton Sharon L et al. · J Agric Food Chem · 2006

PMID: 16417322Preclinical

Enhancing alpha-tocopherol and linoleic acid in ewe's milk by feeding emulsified sunflower oil and DL-alpha-tocopheryl acetate in a chemically treated protein matrix.

Lee Jung Hoon, Waller J C, Melton Sharon L · J Agric Food Chem · 2005

PMID: 16076135Preclinical

Control of dietary energy level and dl-alpha-tocopheryl acetate treatment can improve the lipid composition of lamb meat.

Salvatori Giancarlo, Maiorano Giuseppe, Pantaleo Luigina et al. · Int J Vitam Nutr Res · 2003

PMID: 12847993Preclinical

The efficacy of vitamin E (DL-alpha-tocopheryl acetate) supplementation in hen diets to alleviate egg quality deterioration associated with high temperature exposure.

Kirunda D F, Scheideler S E, McKee S R · Poult Sci · 2001

PMID: 11558926Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: dl-alpha-tocopherol acetate (substance)
SNOMED CT: 812391000168102
UMLS CUI: C0994472

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.