Substance / Medication

Domiphen bromide

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Proarrhythmic effects induced by benzethonium chloride and domiphen bromide in vitro and in vivo.
Long Yan, Hou Jian, Tang Feng et al. · Toxicol Appl Pharmacol · 2021
PMID: 34592322Observational
Molecular determinants of HERG potassium channel blockade by domiphen bromide and benzethonium chloride.
Tang Feng, Lin Zuoxian, Huang Rongqi et al. · Pflugers Arch · 2025
PMID: 40685478Other
Combining Miconazole and Domiphen Bromide Results in Excess of Reactive Oxygen Species and Killing of Biofilm Cells.
Tits Jana, Berman Judith, Cammue Bruno P A et al. · Front Cell Dev Biol · 2020
PMID: 33553152OtherFull text (PMC)
Data on thermal and hydrolytic stability of both domiphen bromide and para-bromodomiphen bromide.
Fumagalli Laura, Moretto Alessandra, Gilardoni Ettore et al. · Data Brief · 2018
PMID: 30246118OtherFull text (PMC)
Stressed degradation studies of domiphen bromide by LC-ESI-MS/MS identify a novel promising antimicrobial agent.
Fumagalli Laura, Regazzoni Luca Giovanni, Straniero Valentina et al. · J Pharm Biomed Anal · 2018
PMID: 29990889Other
Combining with domiphen bromide restores colistin efficacy against colistin-resistant Gram-negative bacteria in vitro and in vivo.
Chen Huanchang, Hu Panjie, Liu Haifeng et al. · Int J Antimicrob Agents · 2024
PMID: 38135012Preclinical
Combination of Miconazole and Domiphen Bromide Is Fungicidal against Biofilms of Resistantspp.
Tits Jana, Cools Freya, De Cremer Kaat et al. · Antimicrob Agents Chemother · 2020
PMID: 32690639PreclinicalFull text (PMC)
Inhibition of HERG potassium channels by domiphen bromide and didecyl dimethylammonium bromide.
Long Yan, Chen Wanjuan, Lin Zuoxian et al. · Eur J Pharmacol · 2014
PMID: 24846011PreclinicalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Domiphen bromide (substance)
SNOMED CT
396034008
UMLS CUI
C0114827

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.