Substance / Medication

Doxepin hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

48 trials linked to this intervention

48
Total Trials
5
Recruiting
17
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Novel therapeutic usage of low-dose doxepin hydrochloride.
Singh Haramandeep, Becker Philip M · Expert Opin Investig Drugs · 2007
PMID: 17685877Review
A double layer oral film loaded with doxepin hydrochloride for the treatment of chemotherapy-induced oral mucositis.
Wang Peiyan, Wang Tianlu, Zhang Hui et al. · Front Pharmacol · 2025
PMID: 41181602OtherFull text (PMC)
Unlocking the secrets of doxepin hydrochloride's crystal structure: Insights from high-quality powder diffraction analysis.
Dezena Renan Marcel Bonilha, Rosa Paulo César Pires · Ann Pharm Fr · 2024
PMID: 37884079Other
In-vitro antiviral activity of doxepin hydrochloride against group B coxsackievirus.
Yang Yongqi, Liu Ge, Jia Jiaoyan et al. · Virus Res · 2022
PMID: 35598772Other
Spectrofluorimetric method for the determination of doxepin hydrochloride in commercial dosage forms.
Rahman Nafisur, Siddiqui Sana, Azmi Syed Najmul Hejaz · AAPS PharmSciTech · 2009
PMID: 19936937OtherFull text (PMC)
[Spectrometric study on the interaction of doxepin hydrochloride and fast green and its application].
Wu Cheng-ke, Feng Su-ling, Fan Jing · Guang Pu Xue Yu Guang Pu Fen Xi · 2007
PMID: 18330292Other
Anti-inflammatory effects of doxepin hydrochloride against LPS-induced C6-glioma cell inflammatory reaction by PI3K-mediated Akt signaling.
Tao Feng, Zhu Jie, Duan Lijie et al. · J Biochem Mol Toxicol · 2020
PMID: 31743544Preclinical
Study of the interaction between doxepin hydrochloride and bovine serum albumin by spectroscopic techniques.
Kandagal P B, Seetharamappa J, Ashoka S et al. · Int J Biol Macromol · 2006
PMID: 16678251Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Doxepin hydrochloride (substance)
SNOMED CT
85037008
UMLS CUI
C0700535

Clinical Data

This intervention maps to 18 entities in the Ltrl knowledge graph.

5
Conditions
6
Biomarkers
4
Specialists
0
Symptoms
48
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.