Substance / Medication

Edetate disodium

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

19 trials linked to this intervention

19
Total Trials
2
Recruiting
7
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Differential Outcomes With Edetate Disodium-Based Treatment Among Stable Post Anterior vs. Non-Anterior Myocardial Infarction Patients.
Lewis Eldrin F, Ujueta Francisco, Lamas Gervasio A et al. · Cardiovasc Revasc Med · 2020
PMID: 32303436RCT
Enhanced vasculotoxic metal excretion in post-myocardial infarction patients following a single edetate disodium-based infusion.
Arenas Ivan A, Navas-Acien Ana, Ergui Ian et al. · Environ Res · 2017
PMID: 28689036RCT
Edetate Disodium-Based Chelation for Patients With a Previous Myocardial Infarction and Diabetes: TACT2 Randomized Clinical Trial.
Lamas Gervasio A, Anstrom Kevin J, Navas-Acien Ana et al. · JAMA · 2024
PMID: 39141382ObservationalFull text (PMC)
In pediatric fatality, edetate disodium was no accident.
Atwood Kimball C, Woeckner Elizabeth · Clin Toxicol (Phila) · 2009
PMID: 19274502Case Report
Deaths resulting from hypocalcemia after administration of edetate disodium: 2003-2005.
Brown Mary Jean, Willis Teresa, Omalu Bennet et al. · Pediatrics · 2006
PMID: 16882789Case Report
Laryngospasm and paradoxical bronchoconstriction after repeated doses of beta 2-agonists containing edetate disodium.
Mutlu G M, Moonjelly E, Chan L et al. · Mayo Clin Proc · 2000
PMID: 10725956Case Report
Urinary Metal Levels after Repeated Edetate Disodium Infusions: Preliminary Findings.
Alam Zenith H, Ujueta Francisco, Arenas Ivan A et al. · Int J Environ Res Public Health · 2020
PMID: 32610666TrialFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Edetate disodium (substance)
SNOMED CT
387418006
UMLS CUI
C0012695

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
19
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.