Substance / Medication

Estradiol valerate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

78 trials linked to this intervention

78
Total Trials
14
Recruiting
23
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Estradiol Valerate vs Ethinylestradiol in Combined Oral Contraceptives: Effects on the Pituitary-Ovarian Axis.
Haverinen Annina, Luiro Kaisu, Kangasniemi Marika H et al. · J Clin Endocrinol Metab · 2022
PMID: 35279718RCT
Combined oral contraceptives containing estradiol valerate vs ethinylestradiol on coagulation: A randomized clinical trial.
Haverinen Annina H, Luiro Kaisu M, Szanto Timea et al. · Acta Obstet Gynecol Scand · 2022
PMID: 35909329RCTFull text (PMC)
Ethinyl estradiol vs estradiol valerate in combined oral contraceptives - Effect on glucose tolerance: A randomized, controlled clinical trial.
Haverinen Annina, Kangasniemi Marika, Luiro Kaisu et al. · Contraception · 2021
PMID: 33098852RCT
Estradiol Valerate in COC Has More Favorable Inflammatory Profile Than Synthetic Ethinyl Estradiol: A Randomized Trial.
Kangasniemi Marika H, Haverinen Annina, Luiro Kaisu et al. · J Clin Endocrinol Metab · 2020
PMID: 32303765RCT
Effect of estradiol valerate on endometrium thickness during clomiphene citrate-stimulated ovulation.
Satirapod Chonthicha, Wingprawat Siripen, Jultanmas Rattiya et al. · J Obstet Gynaecol Res · 2014
PMID: 23937319RCT
Cycle scheduling for in vitro fertilization with oral contraceptive pills versus oral estradiol valerate: a randomized, controlled trial.
Hauzman Erik E, Zapata Azucena, Bermejo Alfonso et al. · Reprod Biol Endocrinol · 2013
PMID: 24074027RCTFull text (PMC)
Oestradiol valerate pretreatment in GnRH-antagonist cycles: a randomized controlled trial.
Blockeel Christophe, Engels Sara, De Vos Michel et al. · Reprod Biomed Online · 2012
PMID: 22296973RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Estradiol valerate (substance)
SNOMED CT
96350008
UMLS CUI
C0059623

Clinical Data

This intervention maps to 13 entities in the Ltrl knowledge graph.

7
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
78
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.