Substance / Medication

Filgrastim

Overview

Active Ingredient
filgrastim
RxNorm CUI
68442
Labeler: Tanvex BioPharma USA, Inc.Updated: 2026-01-15T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Warnings and Precautions (5.3) [see]. NYPOZI is contraindicated in patients with a history of serious allergic reactions to human granulocyte colony-stimulating factors such as filgrastim products or pegfilgrastim products

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Pegfilgrastim safety and efficacy on the last chemotherapy day versus the next: systematic review and meta-analysis.
Ma Xiaohua, Kang Jian, Li Yufang et al. · BMJ Support Palliat Care · 2025
PMID: 34045224Meta-Analysis
Pegfilgrastim on febrile neutropenia in pediatric and adolescent cancer patients: a systematic review and meta-analysis.
Zhu Xia, Zhang Weiling, Zhang Yi et al. · Hematology · 2023
PMID: 36719297Meta-Analysis
Cost-effectiveness of pegfilgrastim versus filgrastim for prevention of chemotherapy-induced febrile neutropenia in patients with lymphoma: a systematic review.
Gebremariam Girma Tekle, Fentie Atalay Mulu, Beyene Kebede et al. · BMC Health Serv Res · 2022
PMID: 36585648Meta-AnalysisFull text (PMC)
Pooled Analysis on the Effectiveness and Safety of Lipegfilgrastim in Patients With Urological Malignancies in the Real-World Setting.
Merseburger Axel S, Geiges Götz, Klier Jörg et al. · Front Oncol · 2021
PMID: 34123810Meta-AnalysisFull text (PMC)
Meta-analysis of Pharmacokinetic/Pharmacodynamic Results of 3 Phase 1 Studies with Biosimilar Pegfilgrastim.
Gattu Sreekanth, Wang Jessie, Bellon Anne et al. · Clin Pharmacol Drug Dev · 2021
PMID: 34350732Meta-AnalysisFull text (PMC)
Clinical role of filgrastim in the management of patients at risk of prolonged severe neutropenia: An evidence-based review.
Bongiovanni Alberto, Recine Federica, Fausti Valentina et al. · Int J Clin Pract · 2019
PMID: 31408256Meta-Analysis
A systematic literature review of the efficacy, effectiveness, and safety of filgrastim.
Dale David C, Crawford Jeffrey, Klippel Zandra et al. · Support Care Cancer · 2018
PMID: 28939926Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Filgrastim (substance)
SNOMED CT
386948008
UMLS CUI
C0210630
RxNorm CUI
68442
Labeler
Tanvex BioPharma USA, Inc.

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.