Substance / Medication

Furosemide

Overview

Active Ingredient
furosemide
RxNorm CUI
4603

Indications

Oral furosemide may be used in adults for the treatment of hypertension alone or in combination with other antihypertensive agents. Hypertensive patients who cannot be adequately controlled with thiazides will probably also not be adequately controlled with furosemide alone.

Labeler: NuCare Pharmaceuticals,Inc.Updated: 2026-02-19T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Furosemide tablets are contraindicated in patients with anuria and in patients with a history of hypersensitivity to furosemide.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

12 trials linked to this intervention

12
Total Trials
2
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Subcutaneous furosemide in heart failure: a systematic review.
Osmanska Joanna, Petrie Mark C, Docherty Kieran F et al. · Eur Heart J Cardiovasc Pharmacother · 2025
PMID: 39520561Meta-AnalysisFull text (PMC)
Torsemide vs. furosemide in congestive heart failure: a systematic-review and meta-analysis on mortality and rehospitalization.
Gudushauri Nino, Polintan Edgar Theodore, Lemonjava Irakli et al. · Acta Cardiol · 2025
PMID: 39910952Meta-Analysis
Efficacy and safety of torsemide versus furosemide in heart failure patients: A systematic review of randomized controlled trials.
Ahmad Cheema Huzaifa, Azeem Saleha, Ejaz Abdullah et al. · Clin Cardiol · 2024
PMID: 37608566Meta-AnalysisFull text (PMC)
The Role of Subcutaneous Furosemide in Heart Failure Management: A Systematic Review.
Widiarti Wynne, Saputra Pandit Bagus Tri, Ariyanto Melissa Valentina et al. · Curr Cardiol Rep · 2024
PMID: 39352583Meta-AnalysisFull text (PMC)
The diuretic effect of adding aminophylline or theophylline to furosemide in pediatric populations: a systematic review.
Van Siang Lian Mang Paul, Hui Jun Chuen, Tan Rachel Si Jing et al. · Eur J Pediatr · 2023
PMID: 36251063Meta-Analysis
Clinical Outcomes With Furosemide Versus Torsemide in Patients With Heart Failure: An Updated Systematic Review and Meta-Analysis.
Siddiqi Ahmed Kamal, Javaid Hira, Ahmed Mushood et al. · Curr Probl Cardiol · 2023
PMID: 37453532Meta-Analysis
Effect of Hypertonic Saline Solution Combined with Furosemide on Acute Heart Failure: A Meta-Analysis.
Li Zuoqing, Wang ZuanJin, Liu Nanchao et al. · Comput Math Methods Med · 2022
PMID: 36188107Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Furosemide (substance)
SNOMED CT
387475002
UMLS CUI
C0016860
RxNorm CUI
4603
Labeler
NuCare Pharmaceuticals,Inc.

Clinical Data

This intervention maps to 16 entities in the Ltrl knowledge graph.

9
Conditions
4
Biomarkers
2
Specialists
0
Symptoms
12
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.