Substance / Medication

Galcanezumab

Overview

Active Ingredient
galcanezumab
RxNorm CUI
2058846
Labeler: Eli Lilly and CompanyUpdated: 2025-10-21T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

5.1 [see Warnings and Precautions ()] EMGALITY is contraindicated in patients with serious hypersensitivity to galcanezumab-gnlm or to any of the excipients.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

4
Total Trials
0
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Real-world effectiveness and safety of galcanezumab for the treatment of migraine: A systematic review and meta-analysis.
Fernández-Bravo-Rodrigo Jaime, Pascual-Morena Carlos, Saz-Lara Alicia et al. · Headache · 2026
PMID: 41246917Meta-Analysis
Efficacy and safety of galcanezumab for cluster headache preventive treatment: a systematic review and meta-analysis.
Barbosa da Silva Marina, Baroni Coelho de Oliveira Ferreira Domênica, Mendieta Cristian D et al. · Neurol Res · 2025
PMID: 39686845Meta-Analysis
Real-world experience of galcanezumab in the prevention of migraine in Spain: a systematic literature review.
Pozo-Rosich Patricia, García-Azorín David, Díaz-Cerezo Silvia et al. · Front Neurol · 2024
PMID: 39639987Meta-AnalysisFull text (PMC)
Efficacy and safety of galcanezumab for migraine: evidences from direct and indirect comparisons.
Wang Xing, Song Jinlei, You Chao · Int J Neurosci · 2023
PMID: 35815440Meta-Analysis
Efficacy and safety of galcanezumab for preventive treatment of migraine: a systematic review and meta-analysis.
Stauffer Virginia L, Oakes Tina M, Rettiganti Mallikarjuna et al. · J Neurol · 2021
PMID: 33590341Meta-Analysis
The treatment efficacy of galcanezumab for migraine: A meta-analysis of randomized controlled trials.
Ren Zhouming, Zhang Hongmei, Wang Ren et al. · Clin Neurol Neurosurg · 2019
PMID: 31581028Meta-Analysis
Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab.
Diener Hans-Christoph, Day Kathleen A, Lipsius Sarah et al. · J Headache Pain · 2025
PMID: 39901101RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Galcanezumab (substance)
SNOMED CT
782371005
UMLS CUI
C4694273
RxNorm CUI
2058846
Labeler
Eli Lilly and Company

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.