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Substance / Medication

Hyoscyamine

SNOMED 372757002 UMLS C0596004

Overview

Active Ingredient

hyoscyamine

RxNorm CUI

153970

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Irritable colon

Hypersecretion of saliva

Intraoperative complication

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

C reactive protein

LOINC 1988-5

secondary

LOINC 770-8

secondary

Clinical Trials

9 trials linked to this intervention

9

Total Trials

0

Recruiting

0

With Results

Recent Trials

A Study Using Botulinum Toxin Type A in Adolescents With Axillary Hyperhidrosis

NCT00168415Phase 4Completed144 enrolled

A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis

NCT00168480Phase 4Completed424 enrolled

Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Terazosin

NCT00449683Phase 4Completed23 enrolled

VASER Treatment of Axillary Hyperhidrosis/Bromidrosis

NCT00735293Phase 4Completed13 enrolled

Outcomes of Phacoemulsification With Torsional Ultrasound

NCT01010490Phase 4Completed360 enrolled

View all 9 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Cine MR enterography grading of small bowel peristalsis: evaluation of the antiperistaltic effectiveness of sublingual hyoscyamine sulfate.

Ghobrial Peter M, Neuberger Ilana, Guglielmo Flavius F et al. · Acad Radiol · 2014

PMID: 24331269RCT

Sublingual hyoscyamine spray as premedication for colonoscopy: a randomized double-blinded placebo-controlled trial.

Chaptini Louis A, Janec Eileen M, Seltzer Gregory et al. · Am J Surg · 2008

PMID: 18436182RCT

Sublingual L-hyoscyamine for duodenal antimotility during ERCP: a prospective randomized double-blinded study.

Lynch Christopher R, Khandekar Suresh, Lynch Scott M et al. · Gastrointest Endosc · 2007

PMID: 17905018RCT

Comparison of two hyoscyamine 6β-hydroxylases in engineering scopolamine biosynthesis in root cultures of Scopolia lurida.

Lan Xiaozhong, Zeng Junlan, Liu Ke et al. · Biochem Biophys Res Commun · 2018

PMID: 29407173Observational

Simultaneous determination of scopolamine, hyoscyamine and anisodamine in in vitro growth media of selected Solanaceae hairy roots by CE method.

Dziomba Szymon, Łepek Teresa, Jaremicz Zbigniew et al. · J Chromatogr B Analyt Technol Biomed Life Sci · 2015

PMID: 26253806Observational

Intra- and inter-laboratory validation of a dipstick immunoassay for the detection of tropane alkaloids hyoscyamine and scopolamine in animal feed.

Mulder Patrick P J, von Holst Christoph, Nivarlet Noan et al. · Food Addit Contam Part A Chem Anal Control Expo Risk Assess · 2014

PMID: 24823431Observational

High-performance liquid-chromatographic tandem-mass spectrometric methods for atropinesterase-mediated enantioselective and chiral determination of R- and S-hyoscyamine in plasma.

John Harald, Eyer Florian, Zilker Thomas et al. · Anal Chim Acta · 2010

PMID: 20969988Observational

HPLC-atmospheric pressure chemical ionization mass spectrometric method for enantioselective determination of R,S-propranolol and R,S-hyoscyamine in human plasma.

Siluk Danuta, Mager Donald E, Gronich Naomi et al. · J Chromatogr B Analyt Technol Biomed Life Sci · 2007

PMID: 17951120Observational

Determination of L-hyoscyamine in atropine and D-hyoscyamine in L-hyoscyamine by chiral capillary electrophoresis as an alternative to polarimetry.

Heine Stephanie, Ebert Kirstin, Blaschke Gottfried · Electrophoresis · 2003

PMID: 12900883Observational

Advanced atrioventricular block due to hypervagotonia: Treatment with hyoscyamine.

Mai William, Kusumoto Fred · HeartRhythm Case Rep · 2022

PMID: 35607346Case ReportFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Internal Medicine Physician

Internal Medicine

NUCC 207R00000X

Gastroenterology Physician

Internal Medicine — Gastroenterology

NUCC 207RG0100X

Find a Provider

Health Goals

Goals connected through associated conditions

Improve Gut Health

Quick Facts

Type: Substance / Medication
Fully Specified Name: Hyoscyamine (substance)
SNOMED CT: 372757002
UMLS CUI: C0596004
RxNorm CUI: 153970

Clinical Data

This intervention maps to 11 entities in the Ltrl knowledge graph.

6

Conditions

2

Biomarkers

2

Specialists

0

Symptoms

9

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.