Substance / Medication

Idoxuridine

Overview

Active Ingredient
idoxuridine
RxNorm CUI
5653

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
The treatment of herpes simplex virus epithelial keratitis.
Wilhelmus K R · Trans Am Ophthalmol Soc · 2000
PMID: 11190039Meta-AnalysisFull text (PMC)
A case report of typhlitis during novel use of ropidoxuridine-capecitabine-radiotherapy for treatment-naïve rectal cancer.
Kunos Charles A, Piekarz Richard, Collins Jerry M et al. · Cancer Chemother Pharmacol · 2023
PMID: 37369852Case ReportFull text (PMC)
[The pathogenesis of herpetic keratitis].
Garweg Justus G, Halberstadt Markus · Klin Monbl Augenheilkd · 2002
PMID: 12195312Review
Synergistic combination effect of cidofovir and idoxuridine on vaccinia virus replication.
Remichkova Mimi, Petrov Nikolay, Galabov Angel S · Antivir Chem Chemother · 2006
PMID: 17042327Preclinical
Topical liposomal gel of idoxuridine for the treatment of herpes simplex: pharmaceutical and clinical implications.
Seth Avinash Kumar, Misra Ambikanandan, Umrigar Dipak · Pharm Dev Technol · 2004
PMID: 15458233Trial
Randomized, open-labelled comparison between an idoxuridine 10% gel and acyclovir 5% cream in recurrent herpes labialis.
Bernard P H, Mounier M, Dupuy P · J Eur Acad Dermatol Venereol · 2003
PMID: 12705773Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Idoxuridine (substance)
SNOMED CT
373499006
UMLS CUI
C0020811
RxNorm CUI
5653

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.