Substance / Medication

Imatinib

Overview

Active Ingredient
imatinib
RxNorm CUI
282388

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

2
Total Trials
1
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of imatinib in patients with COVID-19: a systematic review and meta-analysis.
Li Le, Zhao Chengxiao, Hou Siyuan · Wien Klin Wochenschr · 2025
PMID: 40536568Meta-Analysis
Different outcomes by sex in metastatic gastrointestinal stromal tumor patients receiving imatinib: a trial-level analysis.
Venturino Antonella, Colloca Giuseppe Antonio · Int J Clin Oncol · 2025
PMID: 40488811Meta-Analysis
Published Population Pharmacokinetic Models of Imatinib Perform Poorly on TDM Data from Pediatric Patients.
Yang Tianwu, Rasmussen Anna Sofie Buhl, Weimann Allan et al. · Target Oncol · 2025
PMID: 40920292Meta-AnalysisFull text (PMC)
Evaluating imatinib in severe COVID-19: a systematic review and meta-analysis.
Chagas João Pedro Sarcinelli, de Oliveira Juliana Ribeiro, Brandão Vinicius Andreata et al. · Trans R Soc Trop Med Hyg · 2025
PMID: 39587918Meta-Analysis
Neoadjuvant Imatinib in Recurrent/Metastatic Gastrointestinal Stromal Tumors: A Systematic Review and Meta-analysis of Proportions.
Stavrou Niki, Memos Nikolaos, Filippatos Charalampos et al. · J Gastrointest Cancer · 2025
PMID: 40140195Meta-AnalysisFull text (PMC)
Efficacy and Safety of Treating Pulmonary Arterial Hypertension With Imatinib: A Meta-Analysis of Randomized Controlled Trials.
Chen Xiaofa, Xue Bijuan, Xu Lina · J Cardiovasc Pharmacol · 2025
PMID: 39745285Meta-Analysis
A systematic review and meta-analysis of neoadjuvant imatinib use in locally advanced and metastatic gastrointestinal stromal tumors.
Lam Timothy Jia Rong, Udonwa Shamill Amedot, Masuda Yoshio et al. · World J Surg · 2024
PMID: 38757916Meta-Analysis
The prevalence of hepatic and thyroid toxicity associated with imatinib treatment of chronic myeloid leukaemia: a systematic review.
Tobaiqy Mansour, Helmi Nawal, MacLure Katie et al. · Int J Clin Pharm · 2024
PMID: 38147280Meta-Analysis
Predictive performance of population pharmacokinetic models of imatinib in chronic myeloid leukemia patients.
Dilli Batcha Jaya Shree, Gota Vikram, Matcha Saikumar et al. · Cancer Chemother Pharmacol · 2024
PMID: 38441626Meta-AnalysisFull text (PMC)
Prevalence of Anemia among Chronic Myeloid Leukemia Patients Treated with Imatinib: A Evidence-based Meta-analysis.
Singh Avinash Kumar, Kumar Anoop, Agrawal Narendra et al. · Curr Rev Clin Exp Pharmacol · 2023
PMID: 35293301Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Imatinib (substance)
SNOMED CT
414460008
UMLS CUI
C0935989
RxNorm CUI
282388

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.