Substance / Medication

Imiquimod

Overview

Active Ingredient
imiquimod
RxNorm CUI
59943
Labeler: Sun Pharmaceutical Industries, Inc.Updated: 2026-01-21T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

16 trials linked to this intervention

16
Total Trials
2
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Imiquimod for Anal High Grade Intraepithelial Neoplasia: A Systematic Review.
Gallio Niccolò, Preti Mario, Casetta Elena et al. · Curr Oncol Rep · 2025
PMID: 40387973Meta-AnalysisFull text (PMC)
Off-Label Use of Imiquimod for Lower Female Genital Tract Diseases: A Systematic Review.
Silvestri Flavia, Tosti Giulio, Pepe Francesca et al. · J Low Genit Tract Dis · 2025
PMID: 40576260Meta-Analysis
Imiquimod 5% Cream as an Adjunct to Mohs Micrographic Surgery in Basal Cell Carcinoma: A Mixed Methods Systematic Review.
Aghajani Marra, Savage Alexandra, Bonilla Gilberto Moreno · Dermatol Surg · 2025
PMID: 40326669Meta-Analysis
The efficacy of topical imiquimod in high-grade cervical intraepithelial neoplasia: A systematic review and meta-analysis.
van de Sande A J M, Kengsakul M, Koeneman M M et al. · Int J Gynaecol Obstet · 2024
PMID: 37350560Meta-Analysis
From treatment to trigger: a systematic review of imiquimod-induced psoriasis.
Shah Nirmay, Deol Gursimran, McMullen Eric et al. · Int J Dermatol · 2024
PMID: 38807278Meta-Analysis
Safety and efficacy of the combination of cryotherapy and photodynamic modalities with imiquimod in patients with actinic keratosis: a systematic review and meta-analysis.
Salman Samar, Sarsik Sameh M, El-Qushayri Amr E et al. · Ital J Dermatol Venerol · 2023
PMID: 36799007Meta-Analysis
Imiquimod for Cervical and Vaginal Intraepithelial Neoplasia: A Systematic Review and Meta-analysis.
Inayama Yoshihide, Takamatsu Shiro, Hamanishi Junzo et al. · Obstet Gynecol · 2023
PMID: 37411024Meta-Analysis
Imiquimod for vaginal intraepithelial neoplasia 2-3: A systematic review and meta-analysis.
Inayama Yoshihide, Yamanishi Yukio, Nakatani Eiji et al. · Gynecol Oncol · 2021
PMID: 33010966Meta-Analysis
Imiquimod to prevent keloid recurrence postexcision: A systematic review and meta-analysis.
Klotz Tanja, Munn Zachary, Aromataris Edoardo Claudio et al. · Wound Repair Regen · 2020
PMID: 31587416Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Imiquimod (substance)
SNOMED CT
386941002
UMLS CUI
C0165032
RxNorm CUI
59943
Labeler
Sun Pharmaceutical Industries, Inc.

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
16
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.