Substance / Medication

Insulin glargine

Overview

Active Ingredient
insulin glargine
RxNorm CUI
274783

Indications

® BASAGLARis indicated to improve glycemic control in adults and pediatric patients with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus.

Labeler: Eli Lilly and CompanyUpdated: 2025-12-11T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

BASAGLAR is contraindicated: 5.3 [see Warnings and Precautions ()] During episodes of hypoglycemia. 5.5 [see Warnings and Precautions ()] In patients with hypersensitivity to insulin glargine or any of the excipients in BASAGLAR.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

948 trials linked to this intervention

948
Total Trials
110
Recruiting
300
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of iGlarLixi versus insulin glargine in type 2 diabetes: a meta-analysis of randomized controlled trials.
Li Jingxin, Wang Xiaomin, Wu Jingcheng et al. · Endocrine · 2025
PMID: 40011373Meta-Analysis
Once-Weekly Insulin Icodec. Once-Daily Insulin Glargine U100 for type 2 diabetes: a systematic review and meta-analysis of phase 2 randomized controlled trials.
Ribeiro E Silva Rodrigo, de Miranda Gauza Mateus, Guisso Maria Eduarda Schramm et al. · Arch Endocrinol Metab · 2023
PMID: 37249450Meta-AnalysisFull text (PMC)
Efficacy and safety of insulin glargine 300 units/mL vs insulin degludec in patients with type 1 and type 2 diabetes: a systematic review and meta-analysis.
Alhmoud Eman N, Saad Mohamed Omar, Omar Nabil Elhadi · Front Endocrinol (Lausanne) · 2023
PMID: 38313835Meta-AnalysisFull text (PMC)
Commencing insulin glargine 100 U/mL therapy in individuals with type 2 diabetes: Determinants of achievement of HbA1c goal less than 7.0.
Owens David R, Landgraf Wolfgang, Frier Brian M et al. · Diabetes Obes Metab · 2019
PMID: 30520217Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Insulin glargine (substance)
SNOMED CT
411529005
UMLS CUI
C0907402
RxNorm CUI
274783
Labeler
Eli Lilly and Company

Clinical Data

This intervention maps to 13 entities in the Ltrl knowledge graph.

4
Conditions
4
Biomarkers
3
Specialists
0
Symptoms
948
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.