Substance / Medication

Interferon beta-1a

Overview

Active Ingredient
interferon beta-1a
RxNorm CUI
75917

Indications

AVONEX is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Labeler: Biogen Inc.Updated: 2025-11-19T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

5.3 [see Warnings and Precautions ()] AVONEX is contraindicated in patients with a history of hypersensitivity to natural or recombinant interferon beta, or any other component of the formulation. The formerly available lyophilized vial formulation of AVONEX is contraindicated in patients with a his

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

26 trials linked to this intervention

26
Total Trials
1
Recruiting
14
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Interferon beta-1a for patients with moderate to severe acute respiratory distress syndrome: a systematic review and meta-analysis of randomized trials.
Mammen Manoj J, Aryal Komal, Alhazzani Waleed et al. · Pol Arch Intern Med · 2020
PMID: 32250093Meta-Analysis
Weekly IM interferon beta-1a in multiple sclerosis patients over 50 years of age.
Lampl C, You X, Limmroth V · Eur J Neurol · 2012
PMID: 21718390Meta-Analysis
Nebulised interferon beta-1a (SNG001) in the treatment of viral exacerbations of COPD.
Monk Phillip D, Brookes Jody L, Tear Victoria J et al. · Respir Res · 2024
PMID: 38811970RCTFull text (PMC)
A randomized pharmacokinetic-pharmacodynamic evaluation of the potential biosimilar interferon beta-1a product, CinnoVex®.
Scheinin Mika, Lovró Zsófia, Maadik Inger-Helen et al. · Expert Opin Biol Ther · 2022
PMID: 33678097RCT
Combination therapy with interferon beta-1a and sesame oil in multiple sclerosis.
Faraji Fardin, Hashemi Mahya, Ghiasabadi Atefeh et al. · Complement Ther Med · 2019
PMID: 31331574RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Interferon beta-1a (substance)
SNOMED CT
386902004
UMLS CUI
C0254119
RxNorm CUI
75917
Labeler
Biogen Inc.

Clinical Data

This intervention maps to 6 entities in the Ltrl knowledge graph.

1
Conditions
3
Biomarkers
1
Specialists
0
Symptoms
26
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.