Substance / Medication

Lidocaine

Overview

Active Ingredient
lidocaine
RxNorm CUI
6387

Indications

intact skin Lidocaine patch 5% is indicated for relief of pain associated with post-herpetic neuralgia. It should be applied only to.

Labeler: Sportpharm LLCUpdated: 2026-02-23T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Lidocaine patch 5% is contraindicated in patients with a known history of sensitivity to local anesthetics of the amide type, or to any other component of the product.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

12 trials linked to this intervention

12
Total Trials
1
Recruiting
4
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Topical Lidocaine During Airway Manipulation in Pediatric Anesthesia: A Systematic Review and Meta-Analysis.
Weba Elizabet Taylor Pimenta, de Sousa Gabriel Soares, de Mesquita Ipácio Alexandros Páris et al. · Paediatr Anaesth · 2026
PMID: 41216993Meta-AnalysisFull text (PMC)
Lidocaine patches after cesarean delivery: a meta-analysis of randomized controlled trials.
Parisi Nadia, Petrecca Alessandro, Bender Whitney et al. · Am J Obstet Gynecol MFM · 2026
PMID: 41241094Meta-Analysis
Effectiveness of Adding Dexamethasone to Lidocaine in Upper Limbs Nerve Blocks: A Systematic Review.
Rafiei Mohammad-Reza, Khani Ali Karbalai, Kheradmand Behroz et al. · J Perianesth Nurs · 2025
PMID: 39023476Meta-Analysis
A systematic review and meta-analysis of lidocaine spray efficacy in reducing pain in colposcopy-directed cervical biopsies.
Zahid Subhan, Raza Imran Mansoor, Ahmad Saniya et al. · Eur J Obstet Gynecol Reprod Biol · 2025
PMID: 40561793Meta-Analysis
Lidocaine infusion for the treatment of intractable trigeminal neuralgia: retrospective case series and systematic review.
Mohamed Mohamed Wael, Irem-Oko Francis, Sheikh Asim et al. · Acta Neurochir (Wien) · 2025
PMID: 41021111Meta-AnalysisFull text (PMC)
Effects of intravenous lidocaine on propofol-based sedation in adult patients during gastrointestinal endoscopic procedures: an updated systematic review and meta-analysis.
Rinaldi Pasquale, Galderisi Andrea, Lamacchia Elena Maria et al. · J Clin Anesth · 2025
PMID: 40784173Meta-Analysis
Consensus recommendations for paediatric airway topicalisation using lidocaine.
Iliff Helen A, Parnell Julia, Baker Paul A et al. · Anaesthesia · 2025
PMID: 40717423Meta-AnalysisFull text (PMC)
"Nebulized lidocaine for intractable cough in hospice care: a comprehensive review of efficacy, safety, and future perspectives".
Pan Jumei, Khan Akhtar Ali, Yu Wenkai et al. · BMC Palliat Care · 2025
PMID: 40307800Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Lidocaine (substance)
SNOMED CT
387480006
UMLS CUI
C0023660
RxNorm CUI
6387
Labeler
Sportpharm LLC

Clinical Data

This intervention maps to 10 entities in the Ltrl knowledge graph.

10
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
12
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.