Substance / Medication

Lincomycin

Overview

Active Ingredient
lincomycin
RxNorm CUI
6398

Indications

BOXED WARNING Lincomycin Injection sterile solution is indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci. Its use should be reserved for penicillin-allergic patients or other patients for whom, in the judgment of the physician, a penicillin is inappropriate. Because of the risk of CDAD, as described in the, before selecting lincomycin the physician should consider the nature of the infection and the suitability of other al

Labeler: Slate Run Pharmaceuticals, LLCUpdated: 2023-01-24T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Clostridioides difficile C. difficile. associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including lincomycin injection and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon lead

Contraindications

When this intervention should not be used

Lincomycin Injection is contraindicated in patients previously found to be hypersensitive to lincomycin or clindamycin.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Comparison of lincomycin reaction with manganese oxide under oxic and anoxic environments: Reactivity, Mn speciation and toxicity assessment.
Ying Jiaolong, Qin Xiaopeng, Yan Ni et al. · Ecotoxicol Environ Saf · 2025
PMID: 40945086Observational
Assessing the depletion of lincomycin in feathers from treated broiler chickens: a comparison with the concentration of its residues in edible tissues.
Pokrant Ekaterina, Maddaleno Aldo, Lobos Ramón et al. · Food Addit Contam Part A Chem Anal Control Expo Risk Assess · 2019
PMID: 31535930Observational
Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives.
Kumura Ko, Wakiyama Yoshinari, Ueda Kazutaka et al. · J Antibiot (Tokyo) · 2017
PMID: 27924113Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Lincomycin (substance)
SNOMED CT
372677003
UMLS CUI
C0023726
RxNorm CUI
6398
Labeler
Slate Run Pharmaceuticals, LLC

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.