Substance / Medication

Lispro insulin

Overview

Active Ingredient
insulin lispro
RxNorm CUI
86009

Indications

® LYUMJEVis indicated to improve glycemic control in adult and pediatric patients with diabetes mellitus.

Labeler: Eli Lilly and CompanyUpdated: 2025-12-30T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

LYUMJEV is contraindicated: during episodes of hypoglycemia. in patients with hypersensitivity to insulin lispro-aabc or any of the excipients in LYUMJEV.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

51 trials linked to this intervention

51
Total Trials
1
Recruiting
37
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Use of lispro insulin for treatment of diabetic ketoacidosis in dogs.
Sears Kirk W, Drobatz Kenneth J, Hess Rebecka S · J Vet Emerg Crit Care (San Antonio) · 2012
PMID: 22390184RCT
Multicenter Evaluation of Ultra-Rapid Lispro Insulin with Control-IQ Technology in Adults, Adolescents, and Children with Type 1 Diabetes.
Levy Carol J, Bailey Ryan, Laffel Lori M et al. · Diabetes Technol Ther · 2024
PMID: 38696672ObservationalFull text (PMC)
Lispro insulin in people with non-alcoholic liver cirrhosis and type 2 diabetes mellitus.
Gentile S, Guarino G, Strollo F et al. · Diabetes Res Clin Pract · 2016
PMID: 26803356Observational
Comparison of Subcutaneous Regular Insulin and Lispro Insulin in Diabetics Receiving Continuous Nutrition: A Numerical Study.
Stull Mamie C, Strilka Richard J, Clemens Michael S et al. · J Diabetes Sci Technol · 2015
PMID: 26134836ObservationalFull text (PMC)
A direct comparison of the pharmacodynamic properties of insulin detemir and neutral protamine lispro insulin in patients with type 1 diabetes.
Korsatko S, Glettler K, Olsen K J et al. · Diabetes Obes Metab · 2013
PMID: 23013357Observational
Comparison of lispro insulin and regular insulin in the management of hyperglycaemic emergencies.
Adesina O F, Kolawole B A, Ikem R T et al. · Afr J Med Med Sci · 2011
PMID: 21834263Observational
Glycemic control and perinatal outcomes of pregnancies complicated by type 1 diabetes: influence of continuous subcutaneous insulin infusion and lispro insulin.
Chico Ana, Saigi Ignasi, García-Patterson Apolonia et al. · Diabetes Technol Ther · 2010
PMID: 21128840Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Insulin lispro (substance)
SNOMED CT
412210000
UMLS CUI
C0293359
RxNorm CUI
86009
Labeler
Eli Lilly and Company

Clinical Data

This intervention maps to 13 entities in the Ltrl knowledge graph.

4
Conditions
4
Biomarkers
3
Specialists
0
Symptoms
51
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.