Substance / Medication

Lurbinectedin

Overview

Active Ingredient
lurbinectedin
RxNorm CUI
2374729
Labeler: Jazz Pharmaceuticals, Inc.Updated: 2025-10-02T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Indirect treatment comparison of lurbinectedin versus other second-line treatments for small-cell lung cancer.
Hanvesakul Raj, Rengarajan Badri, Naveh Navit et al. · J Comp Eff Res · 2023
PMID: 37079341Meta-AnalysisFull text (PMC)
Lurbinectedin for extensive stage - small cell lung cancer (ES-SCLC): real world response patterns and survival outcomes.
Krayim Belal, Shalata Walid, Bar Jair et al. · Lung Cancer · 2025
PMID: 40482375Observational
Outcome and safety of lurbinectedin as compassionate use in extensive stage small cell lung cancer: A multicentric international cohort.
Scattolin Daniela, Dingemans Anne-Marie C, Maso Alessandro Dal et al. · Eur J Cancer · 2025
PMID: 40618675Observational
The Use of Lurbinectedin for the Treatment of Small Cell and Neuroendocrine Carcinoma of the Prostate.
Meyer Haley, Sunkara Rajitha, Rothmann Emily et al. · Clin Genitourin Cancer · 2024
PMID: 39232269ObservationalFull text (PMC)
Lurbinectedin in small cell lung cancer: real-world experience of a multicentre national early access programme.
Alexander Marliese, Rogers Jennifer, Parakh Sagun et al. · Intern Med J · 2024
PMID: 38369719Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Lurbinectedin (substance)
SNOMED CT
879925002
UMLS CUI
C3898565
RxNorm CUI
2374729
Labeler
Jazz Pharmaceuticals, Inc.

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.