Substance / Medication

Macrogol 400

Overview

Active Ingredient
polyethylene glycol 400
RxNorm CUI
8514

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

No related conditions have been mapped yet. Condition-intervention linkages are derived from SNOMED CT relationships and will expand as the knowledge graph grows.

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Cost-effectiveness of macrogol 4000 compared to lactulose in the treatment of chronic functional constipation in the UK.
Guest Julian F, Clegg John P, Helter Marianne T · Curr Med Res Opin · 2008
PMID: 18558017Observational
[Anaphylactic shock secondary to the use of macrogol 4000 as a bowel cleanser:a case report].
Ouchi Shohei, Ogiyama Hideharu, Tsutsui Shusaku et al. · Nihon Shokakibyo Gakkai Zasshi · 2019
PMID: 30971670Case Report
Anaphylaxis to macrogol 4000 after a parenteral corticoid injection.
Dewachter Pascale, Mouton-Faivre Claudie · Allergy · 2005
PMID: 15813822Case Report
Use of macrogol 4000 in chronic constipation.
De Giorgio R, Cestari R, Corinaldesi R et al. · Eur Rev Med Pharmacol Sci · 2011
PMID: 21845807Review
Efficacy of macrogol 4000 plus electrolytes in bowel preparation for colonoscopy in patients with chronic constipation.
Ichijima Ryoji, Suzuki Sho, Esaki Mitsuru et al. · BMC Gastroenterol · 2021
PMID: 34666685OtherFull text (PMC)
Polidocanol (Lauromacrogol 400) has anti-angiogenic effects in vitro and in vivo.
Doganci S, Yildirim V, Erol G et al. · Eur Rev Med Pharmacol Sci · 2016
PMID: 27097963Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Macrogol 400 (substance)
SNOMED CT
713360008
UMLS CUI
C0032478
RxNorm CUI
8514

Clinical Data

This intervention maps to 0 entities in the Ltrl knowledge graph.

0
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.