Substance / Medication

Magnesium sulphate

Overview

Active Ingredient
magnesium sulfate
RxNorm CUI
6585

Indications

Sodium sulfate, potassium sulfate and magnesium sulfate oral solution is indicated for cleansing of the colon as a preparation for colonoscopy in adult patients. Pediatric use information is approved for Braintree Laboratories, Inc.’s SUPREP BOWEL PREP KIT (sodium sulfate, potassium sulfate, and magnesium sulfate) oral solution. However, due to Braintree Laboratories, Inc.’s marketing exclusivity rights, this drug product is not labeled with that pediatric information.

Labeler: Camber Pharmaceuticals, Inc.Updated: 2025-01-17T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Warnings and Precautions (5.6) [see] Warnings and Precaution (5.6) [see] Sodium sulfate, potassium sulfate and magnesium sulfate oral solution is contraindicated in the following conditions:• Gastrointestinal obstruction or ileus• Bowel perforation• Toxic colitis or toxic megacolon• Gastric retentio

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

17 trials linked to this intervention

17
Total Trials
2
Recruiting
5
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The efficacy of magnesium sulphate in preventing laryngospasm in paediatric patients undergoing general anaesthesia: A systematic review and meta-analysis of randomised control trials.
Rasheed Mohammad Ahmed, Memon Danyal, Jimenez Clare Keaveney et al. · Anaesth Crit Care Pain Med · 2024
PMID: 39089452Meta-Analysis
Neonatal magnesium sulphate for neuroprotection: A systematic review and meta-analysis.
Shepherd Emily, Karim Tasneem, McIntyre Sarah et al. · Dev Med Child Neurol · 2024
PMID: 38468452Meta-AnalysisFull text (PMC)
Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.
Shepherd Emily S, Goldsmith Shona, Doyle Lex W et al. · Cochrane Database Syst Rev · 2024
PMID: 38726883Meta-AnalysisFull text (PMC)
Alternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia.
Diaz Virginia, Long Qian, Oladapo Olufemi T · Cochrane Database Syst Rev · 2023
PMID: 37815037Meta-AnalysisFull text (PMC)
Is intravenous magnesium sulphate a suitable adjuvant in postoperative pain management? - A critical and systematic review of methodology in randomized controlled trials.
Puch Oernskov Mark, Gaspar Santos Sofia, Sohail Asghar Mohammad et al. · Scand J Pain · 2023
PMID: 36473053Meta-Analysis
Duration of Postpartum Magnesium Sulphate for the Prevention of Eclampsia: A Systematic Review and Meta-analysis.
Okonkwo Maureen, Nash Christopher M · Obstet Gynecol · 2022
PMID: 35271534Meta-Analysis
Magnesium sulphate for treating acute bronchiolitis in children up to two years of age.
Chandelia Sudha, Kumar Dinesh, Chadha Neelima et al. · Cochrane Database Syst Rev · 2020
PMID: 33316083Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Magnesium sulfate (substance)
SNOMED CT
387202002
UMLS CUI
C0024480
RxNorm CUI
6585
Labeler
Camber Pharmaceuticals, Inc.

Clinical Data

This intervention maps to 7 entities in the Ltrl knowledge graph.

7
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
17
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.