Substance / Medication

Memantine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Bioequivalence study of two formulations of memantine hydrochloride tablets in healthy male Chinese subjects under fasting and fed conditions.
Zheng Juntao, Chen Jiangying, Wu Jingjing et al. · Int J Clin Pharmacol Ther · 2020
PMID: 32729819RCT
Application of cocoa butter for formulation of fast melt tablets containing memantine hydrochloride.
Loke Ying Hui, Phang Hiu Ching, Gobal Ganesan et al. · Drug Dev Ind Pharm · 2024
PMID: 39418138Other
Memantine hydrochloride: a drug to be repurposed against Chikungunya virus?
Pereira Anna Karla Dos Santos, Santos Igor A, da Silva Washington W et al. · Pharmacol Rep · 2021
PMID: 33523405OtherFull text (PMC)
Simple Two-step Procedure for the Synthesis of Memantine Hydrochloride from 1,3-Dimethyl-adamantane.
Vu Binh Duong, Ho Ba Ngoc Minh, Pham Van Hien et al. · ACS Omega · 2020
PMID: 32656430OtherFull text (PMC)
A rapid FTIR spectroscopic assay for quantitative determination of Memantine hydrochloride and Amisulpride in human plasma and pharmaceutical formulations.
Atia Noha N, Marzouq Mostafa A, Hassan Ahmed I et al. · Spectrochim Acta A Mol Biomol Spectrosc · 2020
PMID: 32330826Other
A new spectrofluorimetric assay for quantification of Amisulpride and Memantine hydrochloride in real human plasma sample and pharmaceutical formulations via Hantzsch reaction.
Atia Noha N, Marzouq Mostafa A, Hassan Ahmed I et al. · Spectrochim Acta A Mol Biomol Spectrosc · 2020
PMID: 31357052Other
Effect of memantine hydrochloride on cisplatin-induced neurobehavioral toxicity in mice.
Salih Nadia Abdulkareem, Al-Baggou Banan Khalid · Acta Neurol Belg · 2020
PMID: 31190140Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Memantine hydrochloride (substance)
SNOMED CT
426610008
UMLS CUI
C0771988

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.