Substance / Medication

Mephenytoin

Overview

Active Ingredient
mephenytoin
RxNorm CUI
6757

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

92 trials linked to this intervention

92
Total Trials
17
Recruiting
33
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Identification of new CYP2C19 variants exhibiting decreased enzyme activity in the metabolism of S-mephenytoin and omeprazole.
Lee Su-Jun, Kim Woo-Young, Kim Hyunmi et al. · Drug Metab Dispos · 2009
PMID: 19661214Observational
Mephenytoin overdose--phenytoin poisoning incognito? Case report and mephenytoin/phenytoin comparison.
Buchwald A L · J Toxicol Clin Toxicol · 2000
PMID: 11192466Case Report
The effect of perazine on the CYP2D6 and CYP2C19 phenotypes as measured by the dextromethorphan and mephenytoin tests in psychiatric patients.
Baumann Pierre, Eap Chin B, Gastpar Markus · Basic Clin Pharmacol Toxicol · 2020
PMID: 31814297Other
Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity.
Klaassen Tobias, Jetter Alexander, Tomalik-Scharte Dorota et al. · Eur J Clin Pharmacol · 2008
PMID: 18071681Other

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Mephenytoin (substance)
SNOMED CT
28344001
UMLS CUI
C0025381
RxNorm CUI
6757

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
92
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.