Substance / Medication

Methyclothiazide

Overview

Active Ingredient
methyclothiazide
RxNorm CUI
6860

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
PLA2R autoantibodies, a multifaceted biomarker in nephrotic syndrome and membranous nephropathy.
Ragy Omar, Abass Wessam, Kanigicherla Durga Anil K et al. · Nephrol Dial Transplant · 2025
PMID: 39820570Meta-AnalysisFull text (PMC)
Biomarkers to predict or measure steroid resistance in idiopathic nephrotic syndrome: A systematic review.
May Carl J, Ford Nathan P, Welsh Gavin I et al. · PLoS One · 2025
PMID: 39946431Meta-AnalysisFull text (PMC)
Interventions for idiopathic steroid-resistant nephrotic syndrome in children.
Liu Isaac D, Willis Narelle S, Craig Jonathan C et al. · Cochrane Database Syst Rev · 2025
PMID: 40337980Meta-AnalysisFull text (PMC)
Kidney function and mortality in childhood nephrotic syndrome.
Robinson Cal H, Ogome Bess-Joan, Selvathesan Nithiakishna et al. · Nephrol Dial Transplant · 2025
PMID: 40600975Meta-Analysis
Corticosteroid therapy for nephrotic syndrome in children.
Hahn Deirdre, Samuel Susan M, Willis Narelle S et al. · Cochrane Database Syst Rev · 2024
PMID: 39171624Meta-AnalysisFull text (PMC)
Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.
Larkins Nicholas G, Hahn Deirdre, Liu Isaac D et al. · Cochrane Database Syst Rev · 2024
PMID: 39513526Meta-AnalysisFull text (PMC)
[Association of methyclothiazide-triamterene and acute pancreatitis: a case with positive reintroduction].
Stepani P, Mezieres P, Tossou H et al. · Gastroenterol Clin Biol · 2000
PMID: 11084441Case Report
Direct vascular actions of methyclothiazide in remodeled mesenteric arteries from hypertensive patients.
Colas B, Collin T, Safraou F et al. · Am J Hypertens · 2001
PMID: 11710791Other
[Effect of methyclothiazide on the entry of calcium into vascular smooth muscle cells].
Colas B, Colas J L, Masson H et al. · Arch Mal Coeur Vaiss · 2000
PMID: 10989727Preclinical
Mechanisms of methyclothiazide-induced inhibition of contractile responses in rat aorta.
Colas B, Slama M, Collin T et al. · Eur J Pharmacol · 2000
PMID: 11070184Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Methyclothiazide (substance)
SNOMED CT
387373008
UMLS CUI
C0025696
RxNorm CUI
6860

Clinical Data

This intervention maps to 13 entities in the Ltrl knowledge graph.

6
Conditions
4
Biomarkers
2
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.