Substance / Medication

Mexiletine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

12 trials linked to this intervention

12
Total Trials
1
Recruiting
4
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Comparative Analysis of Secondary Outcomes in Treatment of Charcot Neuropathy: A Systematic Review.
Nsekpong Tyler B, Amin Atish S, Ali Shahrukh R et al. · Foot Ankle Spec · 2025
PMID: 35778875Meta-Analysis
[Evaluation of the quality of mexiletine hydrochloride using capillary electrophoreses].
Proksa B, Proksová A · Ceska Slov Farm · 2000
PMID: 10953471Observational
Drug-induced hypersensitivity syndrome due to mexiletine hydrochloride associated with reactivation of human herpesvirus 7.
Yagami Akiko, Yoshikawa Tetsushi, Asano Yoshizo et al. · Dermatology · 2006
PMID: 17135743Case Report
[Intractable hiccups treated with mexiletine hydrochloride].
Ito Hisashi, Yoshika Masamichi, Ohnishi Shizuo et al. · Nihon Naika Gakkai Zasshi · 2003
PMID: 12652738Case Report
Stability assessment of a novel 3D-printed oral dosage form of Mexiletine Hydrochloride: a six-month shelf-life study.
Ait Hoummad Anouar, Ramcharan Arwin, Shokri Fereshteh · Pharm Dev Technol · 2025
PMID: 41239893Other
Designer Gelators for the Crystallization of a Salt Active Pharmaceutical Ingredient-Mexiletine Hydrochloride.
Andrews Jessica L, Kennedy Stuart R, Yufit Dmitry S et al. · Cryst Growth Des · 2022
PMID: 36345390OtherFull text (PMC)
Novel automated assay for the quality control of mexiletine hydrochloride formulations using sequential injection and on-line dilution.
Tzanavaras Paraskevas D, Zacharis Constantinos K, Rigas Pantelis · J Pharm Biomed Anal · 2008
PMID: 18930618Other
Attenuating effect of mexiletine hydrochloride on herpetic pain in mice infected with herpes simplex virus.
Asano Kazuhito, Sameshima Tatsuo, Shirasawa Hiroshi et al. · J Pharm Pharmacol · 2003
PMID: 14607018Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Mexiletine hydrochloride (substance)
SNOMED CT
108500007
UMLS CUI
C0543459

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
12
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.