Substance / Medication

Mycophenolate mofetil

Overview

Active Ingredient
mycophenolate mofetil
RxNorm CUI
68149

Indications

Clinical Studies (14.1) [see], Clinical Studies (14.2) [see] Clinical Studies (14.3) [see] Mycophenolate mofetil tablets are indicated for the prophylaxis of organ rejection, in adult and pediatric recipients 3 months of age and older of allogeneic kidneyheartor liver transplants, in combination with other immunosuppressants.

Labeler: Camber Pharmaceuticals, Inc.Updated: 2026-01-13T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Warnings and Precautions (5.1) Use in Special Populations (8.1 8.3) [see,,]. Warnings and Precautions (5.2) [see]. Warnings and Precautions (5.3) [see • Use during pregnancy is associated with increased risks of first trimester pregnancy loss and congenital malformations. Avoid if safer treatment

Contraindications

When this intervention should not be used

Warnings and Precautions (5.8) [see] Mycophenolate mofetil tablet is contraindicated in patients with a history of hypersensitivity, including anaphylaxis, to mycophenolate mofetil (MMF), mycophenolic acid (MPA) or any component of the drug product.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

145 trials linked to this intervention

145
Total Trials
25
Recruiting
61
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Comparative Effectiveness of Mycophenolate Mofetil and Tacrolimus as a Second-Line Therapy for Autoimmune Hepatitis: A Systematic Review and Meta-Analysis.
Almalki Fahd, Alarmati Sarah T, Shata Razan N et al. · Med Princ Pract · 2025
PMID: 41078044Meta-Analysis
Off-Label Use of Mycophenolate Mofetil in Immunoglobulin A Nephropathy: A Systematic Review and Meta-Analysis.
Feng Luda, Song Xuan, Shi Xinyi et al. · Am J Nephrol · 2025
PMID: 39321787Meta-Analysis
Mycophenolate mofetil versus azathioprine as a first-line treatment for autoimmune hepatitis: a comparative systematic review and meta-analysis.
Ali Amani M, Abdelrahim Mohamed E, AbdelMagid Aya M · BMC Gastroenterol · 2025
PMID: 40846917Meta-AnalysisFull text (PMC)
Comparative Efficacy of Mycophenolate Mofetil vs. Azathioprine in Autoimmune Hepatitis: A Systematic Review and Meta-Analysis.
Ibrahim Momen Mohamed, Sawaf Bisher, Hassan Noheir Ashraf Ibrahem Fathy et al. · Digestion · 2025
PMID: 40875669Meta-AnalysisFull text (PMC)
Efficacy and safety of mycophenolate mofetil in patients with immune thrombocytopenic purpura: a systematic review and meta-analysis.
Abdelwahab Omar Ahmed, Mechi Ahmed, Gahlan Shereen et al. · Clin Rheumatol · 2024
PMID: 37981614Meta-AnalysisFull text (PMC)
Safety and Efficacy of Mycophenolate Mofetil Associated With Tacrolimus for Kidney-pancreas and Kidney Transplantation: A Systematic Review and Meta-Analysis of Randomized Studies.
Datrino Letícia Nogueira, Boccuzzi Matheus Lopes, Silva Rafael Matosinho et al. · Transplant Proc · 2024
PMID: 38853029Meta-Analysis
Treatment of Patients with IgA Nephropathy: Evaluation of the Safety and Efficacy of Mycophenolate Mofetil.
Chen Zaobin, Chen Wenmin, Zheng Lingqian et al. · Curr Pharm Des · 2024
PMID: 38988169Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Mycophenolate mofetil (substance)
SNOMED CT
386976000
UMLS CUI
C0209368
RxNorm CUI
68149
Labeler
Camber Pharmaceuticals, Inc.

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
145
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.