Substance / Medication

Nafcillin

Overview

Active Ingredient
nafcillin
RxNorm CUI
7233

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

135 trials linked to this intervention

135
Total Trials
28
Recruiting
20
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Comparative activities of telavancin combined with nafcillin, imipenem, and gentamicin against Staphylococcus aureus.
Leonard Steven N, Supple Megan E, Gandhi Ronak G et al. · Antimicrob Agents Chemother · 2013
PMID: 23545527ObservationalFull text (PMC)
Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia.
Schweizer Marin L, Furuno Jon P, Harris Anthony D et al. · BMC Infect Dis · 2011
PMID: 22011388ObservationalFull text (PMC)
Higher occurrence of hepatotoxicity and rash in patients treated with oxacillin, compared with those treated with nafcillin and other commonly used antimicrobials.
Maraqa Nizar F, Gomez Margarita M, Rathore Mobeen H et al. · Clin Infect Dis · 2002
PMID: 11731945Observational
Nafcillin and Hypokalemia: A Forgotten Adverse Effect.
Isaac Tambi, Matta Samy, Khan Mahfuza et al. · Cureus · 2025
PMID: 41080379Case ReportFull text (PMC)
Nafcillin-Induced Hepatic Injury: A Case Report and Literature Review.
Khatib Sohaib, Sabobeh Taher, Bock Michael D et al. · Cureus · 2021
PMID: 33628683Case ReportFull text (PMC)
A Case of Hypokalemia Possibly Induced by Nafcillin.
Casado Fernando, Mudunuru Sitarama Arvind, Nasr Rabih · Antibiotics (Basel) · 2018
PMID: 30545049Case ReportFull text (PMC)
Significant drug-drug interaction between warfarin and nafcillin.
King Cynthia A, Babcock Kathleen M, Godios Rhianna J et al. · Ther Adv Drug Saf · 2018
PMID: 30479741Case ReportFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Nafcillin (substance)
SNOMED CT
372898000
UMLS CUI
C0027324
RxNorm CUI
7233

Clinical Data

This intervention maps to 12 entities in the Ltrl knowledge graph.

12
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
135
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.