Substance / Medication

Natamycin

Overview

Active Ingredient
natamycin
RxNorm CUI
7268

Indications

® Fusarium solani in vitro NATACYN(natamycin ophthalmic suspension) 5% is indicated for the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms includingkeratitis. As in other forms of suppurative keratitis, initial and sustained therapy of fungal keratitis should be determined by the clinical diagnosis, laboratory diagnosis by smear and culture of corneal scrapings and drug response. Whenever possible theactivity of natamycin against the responsible fu

Labeler: Eyevance Pharmaceuticals, LLCUpdated: 2025-11-05T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

® NATACYN(natamycin ophthalmic suspension) 5% is contraindicated in individuals with a history of hypersensitivity to any of its components.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

4
Total Trials
0
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Re-appraisal of topical 1% voriconazole and 5% natamycin in the treatment of fungal keratitis in a randomised trial.
Sharma Savitri, Das Sujata, Virdi Ajoy et al. · Br J Ophthalmol · 2015
PMID: 25740805RCT
A novel HPLC method for simultaneous estimation of natamycin and voriconazole for ocular drug delivery applications.
Kailasam Velmurugan, Dasgupta Oindrilla, Mannangatty Tamizhmathy et al. · J Pharm Biomed Anal · 2025
PMID: 39904131Observational
Development of a capillary zone electrophoresis method to determine natamycin in food and a comparison with a liquid chromatography method.
Li Xiaobin, Gao Fangfang, Liu Huitao et al. · J Sci Food Agric · 2020
PMID: 31617212Observational
Niosomes: Do They Increase the Potency of Topical Natamycin Ketorolac Formula in Treating Aspergillus Keratitis? An Experimental Study.
El-Mofty Hala Mohammed, El-Nabarawi Mohamed A, Abd El Rehem Randa Tag et al. · J Ocul Pharmacol Ther · 2020
PMID: 32357092Observational
Natamycin versus voriconazole for fungal keratitis.
Retamal José, Ordenes-Cavieres Gonzalo, Grau-Diez Arturo · Medwave · 2018
PMID: 30562337Observational
Antimicrobial Activity of Nisin and Natamycin Incorporated Sodium Caseinate Extrusion-Blown Films: A Comparative Study with Heat-Pressed/Solution Cast Films.
Colak Basak Yilin, Peynichou Pierre, Galland Sophie et al. · J Food Sci · 2016
PMID: 27061434Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Natamycin (substance)
SNOMED CT
372712006
UMLS CUI
C0027444
RxNorm CUI
7268
Labeler
Eyevance Pharmaceuticals, LLC

Clinical Data

This intervention maps to 17 entities in the Ltrl knowledge graph.

17
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.