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Substance / Medication

Neomycin

SNOMED 373528008UMLS C0027603

Overview

Active Ingredient
neomycin
RxNorm CUI
7299

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Hepatic encephalopathy
Colibacillosis
Bacterial infectious disease
Bacterial infection of skin
Portal systemic encephalopathy

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

4
Total Trials
2
Recruiting
1
With Results

Recent Trials

Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery

NCT03663504Phase 4Active Not Recruiting630 enrolled

Antibiotics and Vaccine Immune Responses Study

NCT06148025Phase 4Recruiting348 enrolled

Responses to Rabies Vaccine in Adults With or Without Antibiotics

NCT03557008Phase 4Completed37 enrolled

Open Study of the Efficacy of the Local Treatment With Polygynax of Bacterial and/or Mycotic Vaginitis

NCT02444481Phase 4Completed169 enrolled
View all 4 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:
Prevalence of Contact Allergy to Neomycin in Dermatitis Patients: A Systematic Review and Meta-Analysis.
Jensen Mikkel Bak, Isufi Daniel, Larsen Christoffer Kursawe et al. · Contact Dermatitis · 2025
PMID: 40107276Meta-AnalysisFull text (PMC)
GC-MS-based metabolomics analysis reveals L-aspartate enhances the antibiotic sensitivity of neomycin sulfate-resistant Aeromonas hydrophila.
Zhao Xianliang, Chen He, Jin Zhaohui et al. · J Fish Dis · 2018
PMID: 30259527RCT
Decolonization of intestinal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae with oral colistin and neomycin: a randomized, double-blind, placebo-controlled trial.
Huttner Benedikt, Haustein Thomas, Uçkay Ilker et al. · J Antimicrob Chemother · 2013
PMID: 23719234RCT
Erythromycin versus neomycin in the treatment of hepatic encephalopathy in cirrhosis: a randomized double-blind study.
Romeiro Fernando Gomes, da Silva Yamashiro Fabio, Américo Madileine Francely et al. · BMC Gastroenterol · 2013
PMID: 23324408RCTFull text (PMC)
Randomized clinical trial of effect of synbiotics, neomycin and mechanical bowel preparation on intestinal barrier function in patients undergoing colectomy.
Reddy B S, Macfie J, Gatt M et al. · Br J Surg · 2007
PMID: 17443852RCT
Ofloxacin otic drops vs neomycin-polymyxin B otic drops as prophylaxis against early postoperative tympanostomy tube otorrhea.
Poetker David M, Lindstrom D Richard, Patel Nalin J et al. · Arch Otolaryngol Head Neck Surg · 2006
PMID: 17178938RCT
Neomycin improves constipation-predominant irritable bowel syndrome in a fashion that is dependent on the presence of methane gas: subanalysis of a double-blind randomized controlled study.
Pimentel Mark, Chatterjee Soumya, Chow Evelyn J et al. · Dig Dis Sci · 2006
PMID: 16832617RCT
Prevalence and Determinants of Sensitisation to Neomycin in North-Eastern Italy, 1997-2021.
Cegolon Luca, Larese Filon Francesca, [object Object] · Contact Dermatitis · 2025
PMID: 39778913ObservationalFull text (PMC)
Oral decontamination with colistin plus neomycin in solid organ transplant recipients colonized by multidrug-resistant Enterobacterales: a multicentre, randomized, controlled, open-label, parallel-group clinical trial.
Fariñas Maria Carmen, González-Rico Claudia, Fernández-Martínez Marta et al. · Clin Microbiol Infect · 2021
PMID: 33359562Observational
Oral neomycin and bacitracin are effective in preventing surgical site infections in elective colorectal surgery: a multicentre, randomized, parallel, single-blinded trial (COLORAL-1).
Arezzo Alberto, Mistrangelo Massimiliano, Bonino Marco Augusto et al. · Updates Surg · 2021
PMID: 34148172ObservationalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Neomycin (substance)
SNOMED CT
373528008
UMLS CUI
C0027603
RxNorm CUI
7299

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.