No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

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Intrathecal nicardipine for cerebral vasospasm after non-traumatic subarachnoid hemorrhage: a meta-analysis.

Lima Natan Lucca, da Silva Mezzari Marcos Henrique, Maggi Bárbara Ghizoni et al. · Neurosurg Rev · 2025

PMID: 40295406Meta-Analysis

Efficacy and safety of nicardipine prolonged-release implants in patients with aneurysmal subarachnoid hemorrhage: A meta-analysis of randomized controlled trials.

Gonçalves Ocílio Ribeiro, Nogueira Luís O S, de Maximiano Mariana Letícia Bastos et al. · Neurosurg Rev · 2025

PMID: 41134407Meta-Analysis

Intravenous nicardipine for Japanese patients with acute intracerebral hemorrhage: an individual participant data analysis.

Toyoda Kazunori, Yoshimura Sohei, Fukuda-Doi Mayumi et al. · Hypertens Res · 2023

PMID: 36224285Meta-AnalysisFull text (PMC)

Comparison between clevidipine and nicardipine in cerebrovascular diseases: A systematic review and meta-analysis.

Seifi Ali, Azari Jafari Amirhossein, Mirmoeeni Seyyedmohammadsadeq et al. · Clin Neurol Neurosurg · 2023

PMID: 36842290Meta-Analysis

Therapeutic and safety outcomes of intracoronary nicardipine in coronary artery disease patients: a systematic review.

Rehan Syeda Tayyaba, Imran Laiba, Salim Aqsa et al. · Future Cardiol · 2023

PMID: 37264944Meta-Analysis

Intensive blood pressure lowering with nicardipine and outcomes after intracerebral hemorrhage: An individual participant data systematic review.

Toyoda Kazunori, Yoshimura Sohei, Fukuda-Doi Mayumi et al. · Int J Stroke · 2022

PMID: 34542358Meta-Analysis

Nicardipine Prolonged Release Implants for Prevention of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis.

Akbik Feras, Waddel Hannah, Jaja Blessing N R et al. · J Stroke Cerebrovasc Dis · 2021

PMID: 34365121Meta-Analysis

Intracranial Administration of Nicardipine After Aneurysmal Subarachnoid Hemorrhage: A Review of the Literature.

Dodson Vincent, Majmundar Neil, El-Ghanem Mohammad et al. · World Neurosurg · 2019

PMID: 30708083Meta-Analysis

Systematic Review of Intrathecal Nicardipine for the Treatment of Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage.

Hafeez Shaheryar, Grandhi Ramesh · Neurocrit Care · 2019

PMID: 30607826Meta-Analysis

The optimal treatment of severe hypertension in pregnancy: update of the role of nicardipine.

Nooij Linda S, Visser Sanne, Meuleman Tess et al. · Curr Pharm Biotechnol · 2014

PMID: 24720593Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Nicardipine (substance)
SNOMED CT: 372502001
UMLS CUI: C0028005
RxNorm CUI: 7396
Labeler: Cipla USA Inc.

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.