Substance / Medication

Nicardipine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

High blood pressure

Prinzmetal angina

Stable angina

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:

Optimization of pH-independent release of nicardipine hydrochloride extended-release matrix tablets using response surface methodology.

Huang Yaw-Bin, Tsai Yi-Hung, Lee Shu-Hui et al. · Int J Pharm · 2005

PMID: 15652202Observational

Successful Recovery from Severe Fever with Thrombocytopenia Syndrome and Hemophagocytic Lymphohistiocytosis with Standard Treatment and a Calcium Channel Blocker of Nicardipine Hydrochloride.

Yamauchi Nao, Hongo Takashi, Kawakami Manri et al. · Intern Med · 2023

PMID: 36171133Case ReportFull text (PMC)

Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 1. Nicardipine hydrochloride for hypertensive crisis in patients with aortic dissection.

Wong Mei-Fwa, Yen Zui-Shen · Emerg Med J · 2011

PMID: 21172915Case Report

Detailed investigation of the spectroscopic features of nicardipine hydrochloride using experimental and quantum chemical methods.

Can Sumeyra, Cinar Mehmet, Baris Ozlem · J Mol Model · 2025

PMID: 41148361Other

Development of an Oral Liquid Formulation of Nicardipine Hydrochloride Compounded with Simple Excipients for the Treatment of Pediatric Hypertension.

Cavelier Marine, Gondé Henri, Costa Damien et al. · Pharmaceutics · 2023

PMID: 36839767OtherFull text (PMC)

Clinical efficacy and safety of two concentrations of intravenous nicardipine hydrochloride for nicardipine-related phlebitis in patients with preeclampsia.

Ye Fengying, Lu Qiuyun, Kong Bihua et al. · Can J Physiol Pharmacol · 2022

PMID: 35213242Other

Development of sustained release gastro-retentive tablet formulation of nicardipine hydrochloride using quality by design (QbD) approach.

Chudiwal Vijay S, Shahi Sadhana, Chudiwal Swapnil · Drug Dev Ind Pharm · 2018

PMID: 29198152Other

Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation.

Zamami Y, Kouno Y, Niimura T et al. · Pharmazie · 2018

PMID: 30522561Other

Encapsulation of Nicardipine Hydrochloride and Release from Biodegradable Poly(D,L-lactic-co-glycolic acid) Microparticles by Double Emulsion Process: Effect of Emulsion Stability and Different Parameters on Drug Entrapment.

Soomherun Nopparuj, Kreua-Ongarjnukool Narumol, Chumnanvej Sorayouth et al. · Int J Biomater · 2017

PMID: 29250113OtherFull text (PMC)

Protective effect of N-acetylcysteine against nicardipine hydrochloride-induced autophagic cell death of human vascular endothelial cells.

Ochi Masanori, Tanaka Yoshiyuki, Toyoda Hiromu · J Toxicol Sci · 2015

PMID: 26354371Other

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Nicardipine hydrochloride (substance)
SNOMED CT: 108527006
UMLS CUI: C0770150

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.