Substance / Medication

Nitazoxanide

Overview

Active Ingredient
nitazoxanide
RxNorm CUI
31819

Indications

Giardia lamblia Cryptosporidium parvum: Diarrhea caused byor Giardia lamblia Cryptosporidium parvum Nitazoxanide tablets (patients 12 years and older) are indicated for the treatment of diarrhea caused byor. Limitations of Use Cryptosporidium parvum [see Clinical Studies (14.2)]. Nitazoxanide tablets have not been shown to be effective for the treatment of diarrhea caused byin HIV-infected or immunodeficient patients

Labeler: e5 Pharma, LLCUpdated: 2026-01-22T00:00:00.000ZFull label on DailyMed

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

5 trials linked to this intervention

5
Total Trials
0
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials.
Martins-Filho Paulo Ricardo, do Nascimento-Júnior Edmundo Marques, Barreto-Alves José Antônio et al. · Eur J Clin Pharmacol · 2022
PMID: 36066651Meta-AnalysisFull text (PMC)
Effect of nitazoxanide on diarrhea: A systematic review and network meta-analysis of randomized controlled trials.
Hashan Mohammad Rashidul, Elhusseiny Khaled Mosaad, Huu-Hoai Le et al. · Acta Trop · 2020
PMID: 32598920Meta-Analysis
Treatment ofwith nitazoxanide-containing regimens: a systematic review.
Lee Sukdong, Sneed Gregory T, Brown Jamie N · Infect Dis (Lond) · 2020
PMID: 31900002Meta-Analysis
Nitazoxanide in the Treatment of Intestinal Parasitic Infections in Children: A Systematic Review and Meta-Analysis.
Li Jinyi, Kuang Hongyu, Zhan Xue · Indian J Pediatr · 2020
PMID: 31833040Meta-Analysis
Nitazoxanide for chronic hepatitis C.
Nikolova Kristiana, Gluud Christian, Grevstad Berit et al. · Cochrane Database Syst Rev · 2014
PMID: 24706397Meta-AnalysisFull text (PMC)
Effect of Nitazoxanide and Probiotic Treatment on Bangladeshi Children with Cryptosporidiosis.
Noor Zannatun, Hossain Biplob, Mithila Nishad Tasnim et al. · Am J Trop Med Hyg · 2025
PMID: 39933176RCTFull text (PMC)
Efficacy and safety of nitazoxanide based quadruple regimen as first line therapy for treating Helicobacter pylori infected naïve patients.
Hassan Amro M, Abdel-Gawad Muhammad, Mahmoud Maie M et al. · J Infect Dev Ctries · 2025
PMID: 40608721RCT
Efficacy and safety of nitazoxanide and escitalopram as adjuvant therapies in patients with rheumatoid arthritis: a randomized controlled study.
Mostafa Tarek M, El-Sayed Abeer A, Afifi Abdel Moaty A et al. · Eur J Clin Pharmacol · 2025
PMID: 40925930RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Nitazoxanide (substance)
SNOMED CT
407148001
UMLS CUI
C0068788
RxNorm CUI
31819
Labeler
e5 Pharma, LLC

Clinical Data

This intervention maps to 6 entities in the Ltrl knowledge graph.

6
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
5
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.