Substance / Medication

Paraldehyde

Overview

Active Ingredient
paraldehyde
RxNorm CUI
7909

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

46 trials linked to this intervention

46
Total Trials
12
Recruiting
12
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Review of the efficacy of rectal paraldehyde in the management of acute and prolonged tonic-clonic convulsions.
Rowland A G, Gill A M, Stewart A B et al. · Arch Dis Child · 2009
PMID: 19357123Observational
DNA-protein cross-link formation in Burkitt lymphoma cells cultured with benzaldehyde and the sedative paraldehyde.
Kuykendall J R, Jarvi E J, Finley B L et al. · Drug Chem Toxicol · 2007
PMID: 17364860Observational
Determination of paraldehyde by gas chromatography in whole blood from children.
Githiga Isaiah M, Muchohi Simon N, Ogutu Bernhards R et al. · J Chromatogr B Analyt Technol Biomed Life Sci · 2004
PMID: 15135115ObservationalFull text (PMC)
RIFM fragrance ingredient safety assessment, paraldehyde, CAS Registry Number 123-63-7.
Api A M, Belsito D, Botelho D et al. · Food Chem Toxicol · 2024
PMID: 38052402Other
Formation of Paraldehyde (CHO) in Interstellar Analog Ices of Acetaldehyde Exposed to Ionizing Radiation.
Wang Jia, Turner Andrew M, Marks Joshua H et al. · Chemphyschem · 2024
PMID: 39363694Other
Paraldehyde as an acetaldehyde precursor in asymmetric Michael reactions promoted by site-isolated incompatible catalysts.
Fan Xinyuan, Rodríguez-Escrich Carles, Sayalero Sonia et al. · Chemistry · 2013
PMID: 23821520Other
Vibrational spectral assignments of paraldehyde by ab initio and density functional methods.
Gunasekaran Sethu, Arunbalaji Ramadoss, Kumaresan Subramanian et al. · J Mol Model · 2008
PMID: 18299903Other
Outcome of status epilepticus in immature rats varies according to the paraldehyde treatment.
Kubová Hana, Rejchrtová Jana, Redkozubova Olga et al. · Epilepsia · 2005
PMID: 15987251Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Paraldehyde (substance)
SNOMED CT
387190006
UMLS CUI
C0030438
RxNorm CUI
7909

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
46
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.