Substance / Medication

Pegademase bovine

Overview

Active Ingredient
pegademase bovine
RxNorm CUI
59768

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

2
Total Trials
2
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
[Current research on severe combined immunodeficiency with transplacental maternal engraftmentt].
Li Wenyan, Deng Kuimiao, Yu Guangyuan et al. · Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · 2025
PMID: 40962442Meta-Analysis
Recommendations for uniform definitions used in newborn screening for severe combined immunodeficiency.
Blom Maartje, Zetterström Rolf H, Stray-Pedersen Asbjørg et al. · J Allergy Clin Immunol · 2022
PMID: 34537207Meta-AnalysisFull text (PMC)
Clinical, Immunological, and Genetic Features in 49 Patients With ZAP-70 Deficiency: A Systematic Review.
Sharifinejad Niusha, Jamee Mahnaz, Zaki-Dizaji Majid et al. · Front Immunol · 2020
PMID: 32431715Meta-AnalysisFull text (PMC)
Meta-analysis of hematopoietic stem cell transplantation in major histocompatibility complex class II deficiency.
Castano-Jaramillo Lina Maria, Bareño-Silva Jose, Tobon Santiago et al. · Pediatr Transplant · 2020
PMID: 32678504Meta-Analysis
TREC Based Newborn Screening for Severe Combined Immunodeficiency Disease: A Systematic Review.
van der Spek Jet, Groenwold Rolf H H, van der Burg Mirjam et al. · J Clin Immunol · 2015
PMID: 25893636Meta-AnalysisFull text (PMC)
Gene therapy as a new treatment option for inherited monogenic diseases.
Boudes Pol F · Eur J Intern Med · 2014
PMID: 24129166Meta-Analysis
Systematic evidence review of newborn screening and treatment of severe combined immunodeficiency.
Lipstein Ellen A, Vorono Sienna, Browning Marsha F et al. · Pediatrics · 2010
PMID: 20403930Meta-Analysis
Identification of severe combined immunodeficiency by T-cell receptor excision circles quantification using neonatal guthrie cards.
Morinishi Yoichi, Imai Kohsuke, Nakagawa Noriko et al. · J Pediatr · 2009
PMID: 19628217RCT
Advances and applications of genome-edited animal models for severe combined immunodeficiency.
Zheng Xiao, Huang Chun-Hui, Yan Sen et al. · Zool Res · 2025
PMID: 39846200ReviewFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pegademase (substance)
SNOMED CT
108743002
UMLS CUI
C0164674
RxNorm CUI
59768

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.