Substance / Medication

Peramivir

Overview

Active Ingredient
peramivir
RxNorm CUI
619693

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Single dose peramivir for the treatment of acute seasonal influenza: integrated analysis of efficacy and safety from two placebo-controlled trials.
Whitley Richard, Laughlin Alan, Carson Simon et al. · Antivir Ther · 2015
PMID: 25318121Meta-Analysis
Intravenous peramivir vs oral oseltamivir in high-risk emergency department patients with influenza: Results from a pilot randomized controlled study.
Hsieh Yu-Hsiang, Dugas Andrea F, LoVecchio Frank et al. · Influenza Other Respir Viruses · 2021
PMID: 33006445RCTFull text (PMC)
[A randomized controlled study of peramivir, oseltamivir and placebo in patients with mild influenza].
Fan H W, Han Y, Liu W et al. · Zhonghua Nei Ke Za Zhi · 2019
PMID: 31365976RCT
Pharmacokinetics of peramivir after single intravenous doses in healthy Chinese subjects.
Zhang Dan, Du Aihua, Zhang Lina et al. · Xenobiotica · 2015
PMID: 25231091RCT
Evaluation of intravenous peramivir for treatment of influenza in hospitalized patients.
de Jong Menno D, Ison Michael G, Monto Arnold S et al. · Clin Infect Dis · 2014
PMID: 25115871RCT
Intravenous peramivir for treatment of influenza in hospitalized patients.
Ison Michael G, Fraiz Joseph, Heller Barry et al. · Antivir Ther · 2014
PMID: 23985625RCT
Absence of pharmacokinetic interaction between intravenous peramivir and oral oseltamivir or rimantadine in humans.
Atiee George, Lasseter Kenneth, Baughman Sharon et al. · J Clin Pharmacol · 2012
PMID: 21960669RCT
Efficacy of a single intravenous dose of the neuraminidase inhibitor peramivir in the treatment of equine influenza.
Yamanaka Takashi, Bannai Hiroshi, Nemoto Manabu et al. · Vet J · 2012
PMID: 22326934RCT
Efficacy and safety of intravenous peramivir for treatment of seasonal influenza virus infection.
Kohno Shigeru, Kida Hiroshi, Mizuguchi Masashi et al. · Antimicrob Agents Chemother · 2010
PMID: 20713668RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Peramivir (substance)
SNOMED CT
716121006
UMLS CUI
C1675326
RxNorm CUI
619693

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.