Substance / Medication

Permethrin

Overview

Active Ingredient
permethrin
RxNorm CUI
33199

Indications

Sarcoptesscabiei Permethrin Cream 5% w/w is indicated for the treatment of infestation with(scabies).

Labeler: REMEDYREPACK INC.Updated: 2026-02-13T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Permethrin Cream 5% w/w is contraindicated in patients with known hypersensitivity to any of its components, to any synthetic pyrethroid or pyrethrin.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

8 trials linked to this intervention

8
Total Trials
3
Recruiting
4
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Ivermectin and permethrin for treating scabies.
Rosumeck Stefanie, Nast Alexander, Dressler Corinna · Cochrane Database Syst Rev · 2018
PMID: 29608022Meta-AnalysisFull text (PMC)
Exposure to permethrin and cancer risk: a systematic review.
Boffetta Paolo, Desai Vimi · Crit Rev Toxicol · 2018
PMID: 29687728Meta-Analysis
Permethrin-Treated Baby Wraps for the Prevention of Malaria.
Boyce Ross M, Shook-Sa Bonnie E, Ndizeye Ronnie et al. · N Engl J Med · 2025
PMID: 40991921RCTFull text (PMC)
Comparison of topical permethrin 5% vs. benzyl benzoate 25% treatment in scabies: a double-blinded randomized controlled trial.
Meyersburg Damian, Hoellwerth Magdalena, Brandlmaier Matthias et al. · Br J Dermatol · 2024
PMID: 38112640RCT
Efficacy of 5% permethrin-2% fusidic acid cream compared to 5% permethrin-placebo in the treatment of impetiginized scabies.
Marina Aninda, Menaldi Sri Linuwih, Novianto Endi et al. · J Infect Dev Ctries · 2022
PMID: 35797300RCT
'Loss of efficacy of topical 5% permethrin for treating scabies: an Austrian single-center study'.
Meyersburg Damian, Kaiser Andreas, Bauer Johann Wolfgang · J Dermatolog Treat · 2022
PMID: 32495666RCT
The Effect of Long-lasting Permethrin Impregnated Socks on Tick Bite in Korea.
Han Mi Ah, Kim Choon Mee, Yun Na Ra et al. · J Korean Med Sci · 2021
PMID: 33619917RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Permethrin (substance)
SNOMED CT
410457007
UMLS CUI
C0070455
RxNorm CUI
33199
Labeler
REMEDYREPACK INC.

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
8
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.