Substance / Medication

Phenoxybenzamine

Overview

Active Ingredient
phenoxybenzamine
RxNorm CUI
8149

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

3 trials linked to this intervention

3
Total Trials
2
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Short-acting urapidil compared to long-acting phenoxybenzamine in the management of pheochromocytoma.
Feld A, Mintziras I, Wächter S et al. · Langenbecks Arch Surg · 2025
PMID: 39934496ObservationalFull text (PMC)
Comparison of phenoxybenzamine and doxazosin in perioperative management of patients with pheochromocytoma.
Malec Klaudia, Miśkiewicz Piotr, Witkowska Agnieszka et al. · Kardiol Pol · 2017
PMID: 28715066Observational
Treatment with phenoxybenzamine may lead to loss of endothelial viability in radial artery.
Pai Remananda Krishnanand, Conant Alan R, Dihmis Walid C · Ann Thorac Surg · 2008
PMID: 18573463Observational
Combination of low-dose phenoxybenzamine and sodium nitroprusside in children undergoing cardiac surgery.
Kiran Usha, Zuber Khalid, Kakani Madhava · J Cardiothorac Vasc Anesth · 2006
PMID: 16616682Observational
Comparison of phenoxybenzamine to sodium nitroprusside in infants undergoing surgery.
Motta Pablo, Mossad Emad, Toscana Diego et al. · J Cardiothorac Vasc Anesth · 2005
PMID: 15747270Observational
[Effects of doxazosin mosylate and phenoxybenzamine in preoperative volume expansion of pheochromocytoma: a comparative study in 38 cases].
Pan Dong-liang, Li Han-zhong, Ji Zhi-gang et al. · Zhonghua Yi Xue Za Zhi · 2005
PMID: 16029653Observational
Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators.
Conant Alan R, Shackcloth Michael J, Oo Aung Y et al. · J Thorac Cardiovasc Surg · 2003
PMID: 12928643Observational
Pretreatment with phenoxybenzamine attenuates the radial artery's vasoconstrictor response to alpha-adrenergic stimuli.
Corvera Joel S, Morris Cullen D, Budde Jason M et al. · J Thorac Cardiovasc Surg · 2003
PMID: 14666031Observational
Phenoxybenzamine is more effective and less harmful than papaverine in the prevention of radial artery vasospasm.
Dipp M A, Nye P C, Taggart D P · Eur J Cardiothorac Surg · 2001
PMID: 11306317Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Phenoxybenzamine (substance)
SNOMED CT
372838003
UMLS CUI
C0031441
RxNorm CUI
8149

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
3
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.