Substance / Medication

Physostigmine

Overview

Active Ingredient
physostigmine
RxNorm CUI
8299

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

1 trials linked to this intervention

1
Total Trials
0
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Physostigmine for Alzheimer's disease.
Coelho F, Birks J · Cochrane Database Syst Rev · 2001
PMID: 11405996Meta-AnalysisFull text (PMC)
Perioperative use of physostigmine to reduce opioid consumption and peri-incisional hyperalgesia: a randomised controlled trial.
Klivinyi Christoph, Rumpold-Seitlinger Gudrun, Dorn Christian et al. · Br J Anaesth · 2021
PMID: 33317802RCT
A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome.
Wang George Sam, Baker Keith, Ng Patrick et al. · Clin Toxicol (Phila) · 2021
PMID: 33295809RCT
A Randomized, Prospective, Double-Blinded Study of Physostigmine to Prevent Sedation-Induced Ventilatory Arrhythmias.
Karan Suzanne B, Rackovsky Elia, Voter William A et al. · Anesth Analg · 2015
PMID: 26200465RCT
The effects of physostigmine on recovery from general anesthesia in elderly patients.
Panagopoulou V, Tzimas P, Arampatzis P et al. · Minerva Anestesiol · 2011
PMID: 21483384RCT
Interaction of physostigmine and alfentanil in a human pain model.
Wehrfritz A P, Ihmsen H, Schmidt S et al. · Br J Anaesth · 2010
PMID: 20047897RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Physostigmine (substance)
SNOMED CT
373347005
UMLS CUI
C0031849
RxNorm CUI
8299

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

2
Conditions
1
Biomarkers
1
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.