Substance / Medication

Pilocarpine

Overview

Active Ingredient
pilocarpine
RxNorm CUI
8328

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

57 trials linked to this intervention

57
Total Trials
26
Recruiting
7
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Short-Term Efficacy and Safety of Pilocarpine Ophthalmic Solution for Presbyopia: A Systematic Review and Meta-Analysis.
Lima Gabriel Nery, Amaral Dillan Cunha, Ivanov Yuri Aleksander et al. · Am J Ophthalmol · 2025
PMID: 40835063Meta-Analysis
Pilocarpine treatment of Sjögren's syndrome curative effect of meta-analysis of randomised controlled trials.
Wu Juan, Li Donsheng · Clin Exp Rheumatol · 2024
PMID: 39699871Meta-Analysis
Systematic review and meta-analysis of the efficacy of different exercise programs in pilocarpine induced status epilepticus models.
Iqbal Muneeb, Rahman Md Saidur, Zafar Salman et al. · Epilepsy Behav · 2017
PMID: 28666249Meta-Analysis
Is Pilocarpine Effective in Preventing Radiation-Induced Xerostomia? A Systematic Review and Meta-analysis.
Yang Wei-fa, Liao Gui-qing, Hakim Samer G et al. · Int J Radiat Oncol Biol Phys · 2016
PMID: 26867879Meta-Analysis
Orally dissolving pilocarpine tablets for xerostomia in advanced cancer: A pilot N-of-1 feasibility study.
Foster Karyn, Mitchell Geoff, Richard Evan et al. · Palliat Med · 2025
PMID: 39717970RCT
Sweat induction using Pilocarpine microneedle patches for sweat testing in healthy adults.
Chen Jonathan Yuxuan, Li Song, Silva George L et al. · J Cyst Fibros · 2024
PMID: 37236899RCT
Impact of presbyopia treatment pilocarpine hydrochloride 1.25% on night-driving performance.
Waring George O, Brujic Mile, McGee Selina et al. · Clin Exp Optom · 2024
PMID: 38044272RCT
As-Needed Pilocarpine for Radiation-Induced Xerostomia in Head and Neck Cancers.
Watanapokasin Natcha, Rawangban Worawat, Tangjaturonrasme Napadon · Laryngoscope · 2024
PMID: 38813852RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pilocarpine (substance)
SNOMED CT
372895002
UMLS CUI
C0031923
RxNorm CUI
8328

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
57
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.