Substance / Medication

Pilocarpine nitrate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

57 trials linked to this intervention

57
Total Trials
26
Recruiting
7
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Is Acupuncture an Effective Treatment for Radiation-Induced Xerostomia of Patients with Head and Neck Cancer? A Systematic Review and Meta-Analysis.
Gu Wenzhe, Dong Hongjun, Yuan Yuan et al. · J Integr Complement Med · 2025
PMID: 39600262Meta-Analysis
Predictive biomarkers of radiotherapy- related dermatitis, xerostomia, mucositis and dysphagia in head and neck cancer: A systematic review.
Koch Alexander, Reinhardt Philipp, Elicin Olgun et al. · Radiother Oncol · 2025
PMID: 39706342Meta-Analysis
A systematic review of salivary gland hypofunction and/or xerostomia induced by non-surgical cancer therapies: prevention strategies.
Mercadante Valeria, Smith Derek K, Abdalla-Aslan Ragda et al. · Support Care Cancer · 2025
PMID: 39792256Meta-AnalysisFull text (PMC)
Design and evaluation of liposomal formulation of pilocarpine nitrate.
Rathod S, Deshpande S G · Indian J Pharm Sci · 2010
PMID: 20838517OtherFull text (PMC)
A Novel Phytantriol-Based Lyotropic Liquid Crystalline Gel for Efficient Ophthalmic Delivery of Pilocarpine Nitrate.
Wang Xingqi, Zhang Yong, Huang Jie et al. · AAPS PharmSciTech · 2019
PMID: 30603986Preclinical
Self-assembled hexagonal liquid crystalline gels as novel ocular formulation with enhanced topical delivery of pilocarpine nitrate.
Wang Xingqi, Zhang Yong, Huang Jie et al. · Int J Pharm · 2019
PMID: 30878587Preclinical
A potential carrier based on liquid crystal nanoparticles for ophthalmic delivery of pilocarpine nitrate.
Li Jing, Wu Lin, Wu Weijun et al. · Int J Pharm · 2013
PMID: 23916822Preclinical
[Chitosan-coated ophthalmic submicro emulsion for pilocarpine nitrate].
Wei Jun, He Hong-Liang, Zheng Chun-Li et al. · Yao Xue Xue Bao · 2011
PMID: 22007526Preclinical
Poly(amidoamine) dendrimers as ophthalmic vehicles for ocular delivery of pilocarpine nitrate and tropicamide.
Vandamme Th F, Brobeck L · J Control Release · 2005
PMID: 15653131Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pilocarpine nitrate (substance)
SNOMED CT
395827004
UMLS CUI
C0351975

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
57
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.