Substance / Medication

Pravastatin

Overview

Active Ingredient
pravastatin
RxNorm CUI
42463

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

34 trials linked to this intervention

34
Total Trials
3
Recruiting
7
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The role of pravastatin in preventing preeclampsia in high-risk pregnant women: a meta-analysis with trial sequential analysis.
Provinciatto Henrique, Barbalho Maria Esther, Almeida Juliana et al. · Am J Obstet Gynecol MFM · 2024
PMID: 38109997Meta-Analysis
Pravastatin for lowering lipids.
Adams Stephen P, Alaeiilkhchi Nima, Tasnim Sara et al. · Cochrane Database Syst Rev · 2023
PMID: 37721222Meta-AnalysisFull text (PMC)
Pravastatin in preeclampsia: A meta-analysis and systematic review.
Mészáros Balázs, Veres Dániel Sándor, Nagyistók Luca et al. · Front Med (Lausanne) · 2022
PMID: 36714131Meta-AnalysisFull text (PMC)
Pravastatin, proton-pump inhibitors, metformin, micronutrients, and biologics: new horizons for the prevention or treatment of preeclampsia.
Tong Stephen, Kaitu'u-Lino Tu'uhevaha J, Hastie Roxanne et al. · Am J Obstet Gynecol · 2022
PMID: 32946849Meta-Analysis
Pravastatin and placental insufficiency associated disorders: A systematic review and meta-analysis.
Hirsch Ayala, Rotem Reut, Ternovsky Natali et al. · Front Pharmacol · 2022
PMID: 36438820Meta-AnalysisFull text (PMC)
Effect of pravastatin treatment on circulating adiponectin: a meta-analysis of randomized controlled trials.
Shu Xiangrong, Chi Liqun · Drug Des Devel Ther · 2019
PMID: 31190742Meta-AnalysisFull text (PMC)
Pravastatin for Preventing and Treating Preeclampsia: A Systematic Review.
Esteve-Valverde Enrique, Ferrer-Oliveras Raquel, Gil-Aliberas Natàlia et al. · Obstet Gynecol Surv · 2018
PMID: 29368790Meta-Analysis
Long-Term Effectiveness and Safety of Pravastatin in Patients With Coronary Heart Disease: Sixteen Years of Follow-Up of the LIPID Study.
Hague Wendy E, Simes John, Kirby Adrienne et al. · Circulation · 2016
PMID: 27016105Meta-Analysis
Pravastatin use and cancer risk: a meta-analysis of individual patient data from long-term prospective controlled trials in Japan.
Matsushita Yasuyuki, Sugihara Masahiro, Kaburagi Junpei et al. · Pharmacoepidemiol Drug Saf · 2010
PMID: 19856484Meta-Analysis
Does pravastatin promote cancer in elderly patients? A meta-analysis.
Bonovas Stefanos, Sitaras Nikolaos M · CMAJ · 2007
PMID: 17325332Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pravastatin (substance)
SNOMED CT
373566006
UMLS CUI
C0085542
RxNorm CUI
42463

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
34
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.