Substance / Medication

Primaquine

Overview

Active Ingredient
primaquine
RxNorm CUI
8687

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

20 trials linked to this intervention

20
Total Trials
0
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Single low-dose primaquine for malaria control in Africa: a systematic review of safety, efficacy and implementation barriers.
Ye Tianle, Caspar Emmanuelle, Niyomwungere Denis et al. · BMJ Glob Health · 2025
PMID: 40813102Meta-AnalysisFull text (PMC)
Primaquine for uncomplicated Plasmodium vivax malaria in children younger than 15 years: a systematic review and individual patient data meta-analysis.
Commons Robert J, Rajasekhar Megha, Allen Elizabeth N et al. · Lancet Child Adolesc Health · 2024
PMID: 39332427Meta-AnalysisFull text (PMC)
Safety and efficacy of primaquine in patients withmalaria from South Asia: a systematic review and individual patient data meta-analysis.
Verma Reena, Commons Robert J, Gupta Apoorv et al. · BMJ Glob Health · 2023
PMID: 38123228Meta-Analysis
Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data.
Stepniewska Kasia, Allen Elizabeth N, Humphreys Georgina S et al. · BMC Med · 2022
PMID: 36109733Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Primaquine (substance)
SNOMED CT
429663004
UMLS CUI
C0033126
RxNorm CUI
8687

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
20
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.